Porphyrin-Based Carbon Dots for Photodynamic Therapy of Hepatoma

被引：150
作者：
Li, Yang [1 ,2 ]
Zheng, Xiaohua [1 ,3 ]
Zhang, Xiaoyu [2 ]
Liu, Shi [1 ]
Pei, Qing [1 ,3 ]
Zheng, Min [4 ]
Xie, Zhigang [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Chem & Phys, 5625 Renmin St, Changchun 130022, Jilin, Peoples R China
[2] Yanshan Univ, Coll Environm & Chem Engn, 438 Heibei Ave, Qinhuangdao 066004, Hebei, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[4] Changchun Univ Technol, Sch Chem & Life Sci, Adv Inst Mat Sci, 2055 Yanan St, Changchun 130012, Jilin, Peoples R China
来源：
ADVANCED HEALTHCARE MATERIALS | 2017年 / 6卷 / 01期
基金：
中国国家自然科学基金;
关键词：
AGGREGATION-INDUCED EMISSION; QUANTUM DOTS; CANCER RECURRENCE; CANINE PROSTATE; NANOPARTICLES; FLUORESCENT; PHTHALOCYANINE; THERANOSTICS; COPOLYMERS; AUTOPHAGY;
D O I：
10.1002/adhm.201600924
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Porphyrin-containing carbon dots (CDs) possess ultrasmall size, excellent water solubility, and photostability. These CDs can effectively generate cytotoxic singlet oxygen upon irradiation, and induce the cell apoptosis. Photodynamic ability of CDs inhibits the growth of hepatoma. This work not only sheds light on developing functional carbon dots, but also highlights the importance of special-structure precursor molecules in synthesizing functional CDs.
引用
收藏
页数：6
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