The cytokine storm-An appropriate, over-reactive response to SARS-CoV-2 or the wrong immune pathway?

被引：7
作者：
Bellgrau, Donald [1 ]
Modiano, Jaime F. [2 ]
机构：
[1] Univ Colorado, Sch Med, Aurora, CO 80045 USA
[2] Univ Minnesota, Coll Vet Med, St Paul, MN 55108 USA
来源：
SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 2021年 / 93卷 / 03期
关键词：
COVID-19; cytokine storm; SARS-CoV-2;
D O I：
10.1111/sji.12979
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：2
相关论文
共 10 条
  • [1] Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
    Blanco-Melo, Daniel
    Nilsson-Payant, Benjamin E.
    Liu, Wen-Chun
    Uhl, Skyler
    Hoagland, Daisy
    Moller, Rasmus
    Jordan, Tristan X.
    Oishi, Kohei
    Panis, Maryline
    Sachs, David
    Wang, Taia T.
    Schwartz, Robert E.
    Lim, Jean K.
    Albrecht, Randy A.
    tenOever, Benjamin R.
    [J]. CELL, 2020, 181 (05) : 1036 - +
  • [2] Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic
    Boni, Maciej F.
    Lemey, Philippe
    Jiang, Xiaowei
    Lam, Tommy Tsan-Yuk
    Perry, Blair W.
    Castoe, Todd A.
    Rambaut, Andrew
    Robertson, David L.
    [J]. NATURE MICROBIOLOGY, 2020, 5 (11) : 1408 - +
  • [3] Molecular Basis of Coronavirus Virulence and Vaccine Development
    Enjuanes, L.
    Zuniga, S.
    Castano-Rodriguez, C.
    Gutierrez-Alvarez, J.
    Canton, J.
    Sola, I.
    [J]. ADVANCES IN VIRUS RESEARCH, VOL 96: CORONAVIRUSES, 2016, 96 : 245 - 286
  • [4] Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
    Jamilloux, Yvan
    Henry, Thomas
    Belot, Alexandre
    Viel, Sebastien
    Fauter, Maxime
    El Jammal, Thomas
    Walzer, Thierry
    Francois, Bruno
    Seve, Pascal
    [J]. AUTOIMMUNITY REVIEWS, 2020, 19 (07)
  • [5] Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19
    Kaneko, Naoki
    Kuo, Hsiao-Hsuan
    Boucau, Julie
    Farmer, Jocelyn R.
    Allard-Chamard, Hugues
    Mahajan, Vinay S.
    Piechocka-Trocha, Alicja
    Lefteri, Kristina
    Osborn, Matthew
    Bals, Julia
    Bartsch, Yannic C.
    Bonheur, Nathalie
    Caradonna, Timothy M.
    Chevalier, Josh
    Chowdhury, Fatema
    Diefenbach, Thomas J.
    Einkauf, Kevin
    Fallon, Jon
    Feldman, Jared
    Finn, Kelsey K.
    Garcia-Broncano, Pilar
    Hartana, Ciputra Adijaya
    Hauser, Blake M.
    Jiang, Chenyang
    Kaplonek, Paulina
    Karpell, Marshall
    Koscher, Eric C.
    Lian, Xiaodong
    Liu, Hang
    Liu, Jinqing
    Ly, Ngoc L.
    Michell, Ashlin R.
    Rassadkina, Yelizaveta
    Seiger, Kyra
    Sessa, Libera
    Shin, Sally
    Singh, Nishant
    Sun, Weiwei
    Sun, Xiaoming
    Ticheli, Hannah J.
    Waring, Michael T.
    Zhu, Alex L.
    Alter, Galit
    Li, Jonathan Z.
    Lingwood, Daniel
    Schmidt, Aaron G.
    Lichterfeld, Mathias
    Walker, Bruce D.
    Yu, Xu G.
    Padera, Robert F., Jr.
    [J]. CELL, 2020, 183 (01) : 143 - +
  • [6] Lei X, 2020, NAT COMMUN, V11, P1, DOI DOI 10.1038/S41467-019-13993-7
  • [7] Type I IFN-mediated regulation of IL-1 production in inflammatory disorders
    Ludigs, Kristina
    Parfenov, Valeriy
    Du Pasquier, Renaud A.
    Guarda, Greta
    [J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2012, 69 (20) : 3395 - 3418
  • [8] Cytokine release syndrome in severe COVID-19
    Moore, John B.
    June, Carl H.
    [J]. SCIENCE, 2020, 368 (6490) : 473 - 474
  • [9] Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?
    Ritchie, Andrew I.
    Singanayagam, Aran
    [J]. LANCET, 2020, 395 (10230) : 1111 - 1111
  • [10] The Immunobiology of the Interleukin-12 Family: Room for Discovery
    Wojno, Elia D. Tait
    Hunter, Christopher A.
    Stumhofer, Jason S.
    [J]. IMMUNITY, 2019, 50 (04) : 851 - 870
1