Differential regulation of the two metallothionein genes in common carp

被引：7

作者：

Hermesz, E ^{[1
]}

Gazdag, AP ^{[1
]}

Ali, KS ^{[1
]}

Nemcsók, J ^{[1
]}

Abrahám, M ^{[1
]}

机构：

[1] Univ Szeged, Fac Sci, Dept Biochem, H-6701 Szeged, Hungary

来源：

ACTA BIOLOGICA HUNGARICA | 2002年 / 53卷 / 03期

关键词：

carp; gene expression; metallothionein mRNAs; metal treatment; RT-PCR;

D O I：

10.1556/ABiol.53.2002.3.11

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The expression of two metallothionein (MT) genes was followed in carp (Cyprinus carpio) in vivo during exposure to As and Cu. Changes in the levels of MT-1 and MT-2 mRNA in the liver and kidney were detected by semi-quantitative RT-PCR. The inducibility of the two MT isoforms was tissue- and metal-specific. Regardless of whether As or Cu was applied, the liver was more responsive than the kidney. Copper influenced the expression of both isoforms: the MT-1 and MT-2 mRNA levels increased in both the liver and the kidney in a time- and dose-dependent manner. Arsenic affected mostly the MT-2 expression, while the level of the MT-1 transcript did not change significantly in either organ.

引用

页码：343 / 350

页数：8

共 50 条

[41] Re-evaluation of common carp (Cyprinus carpio L.) housekeeping genes for gene expression studies - considering duplicated genes
Szczygiel, Joanna
Kaminska-Gibas, Teresa
Petit, Jules
Jurecka, Patrycja
Wiegertjes, Geert
Irnazarow, Ilgiz
FISH & SHELLFISH IMMUNOLOGY, 2021, 115 : 58 - 69
[42] Role of sox30 in regulating testicular steroidogenesis of common carp
Anitha, Arumugam
Senthilkumaran, Balasubramanian
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2020, 204
[43] Differential regulation of expression of the mammalian DNA repair genes by growth stimulation
Ritsuko Iwanaga
Hideyuki Komori
Kiyoshi Ohtani
Oncogene, 2004, 23 : 8581 - 8590
[44] Osmoregulatory Genes Expression Analysis and Chloride Cells Activity in Common Carp: Insight from Fish Exposed to Salinity
Emeish, Walaa F. A.
Soliman, Soha A.
Ahmed, Ahmed Ezzat
Alsaegh, Aiman A.
Alsyaad, Khalid M.
Ali, Montaser Elsayed
Ahmed, Hassan
PAKISTAN VETERINARY JOURNAL, 2023, 43 (03) : 515 - 522
[45] Differential regulation of expression of the mammalian DNA repair genes by growth stimulation
Iwanaga, R
Komori, H
Ohtani, K
ONCOGENE, 2004, 23 (53) : 8581 - 8590
[46] Differential regulation of manganese peroxidases and characterization of two variable MnP encoding genes in the white-rot fungus Physisporinus rivulosus
Hakala, Terhi K.
Hilden, Kristiina
Maijala, Pekka
Olsson, Cia
Hatakka, Annele
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 73 (04) : 839 - 849
[47] Carp edema virus from three genogroups is present in common carp in Hungary
Adamek, M.
Baska, F.
Vincze, B.
Steinhagen, D.
JOURNAL OF FISH DISEASES, 2018, 41 (03) : 463 - 468
[48] Differential regulation of manganese peroxidases and characterization of two variable MnP encoding genes in the white-rot fungus Physisporinus rivulosus
Terhi K. Hakala
Kristiina Hildén
Pekka Maijala
Cia Olsson
Annele Hatakka
Applied Microbiology and Biotechnology, 2006, 73 : 839 - 849
[49] Diversification of the duplicated Rab1a genes in a hypoxia-tolerant fish, common carp (Cyprinus carpio)
Zhao, Zi-Xia
Cao, Ding-Chen
Xu, Jian
Xu, Ru
Li, Jiong-Tang
Zhang, Yan
Xu, Peng
Sun, Xiao-Wen
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2015, 188 : 54 - 62
[50] Two new members of the Tetrahymena multi-stress-inducible metallothionein family: Characterization and expression analysis of T-rostrata Cd/Cu metallothionein genes
Amaro, Francisco
del Pilar de Lucas, Maria
Martin-Gonzalez, Ana
Gutierrez, Juan Carlos
GENE, 2008, 423 (01) : 85 - 91

← 1 2 3 4 5 →