Synthesis and crystal structure of new heterocycles containing 1,2,4-oxadiazole, 1,2,4-oxadiazolone (thione), hydantoin, and mercaptobenzimidazole units

被引：1
作者：
Durust, Yasar [1 ]
Gozlukaya, Ozge [1 ]
Ozer, Gulsun [1 ]
Fronczek, Frank R. [2 ]
机构：
[1] Abant Izzet Baysal Univ, Dept Chem, TR-14280 Bolu, Turkey
[2] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA
来源：
MOLECULAR DIVERSITY | 2014年 / 18卷 / 03期
关键词：
Oxadiazole; Oxadiazolone(thione); Hydantoin; Mercapto benzimidazole; BIOLOGICAL-ACTIVITY; DERIVATIVES; POTENT; RECEPTOR; OXADIAZOLES; THIOPHENE; AGONISTS;
D O I：
10.1007/s11030-014-9525-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A number of 1,2,4-oxadiazolone and mercapto nitro benzimidazole derivatives containing 1,2,4-oxadiazole and hydantoin moieties have been prepared, and their structures were identified by means of spectral/physical characteristics including X-ray diffraction data.
引用
收藏
页码：545 / 558
页数：14
相关论文
共 50 条
  • [41] Structure and Cytotoxicity of Phidianidines A and B: First Finding of 1,2,4-Oxadiazole System in a Marine Natural Product
    Carbone, Marianna
    Li, Yan
    Irace, Carlo
    Mollo, Ernesto
    Castelluccio, Francesco
    Di Pascale, Antonio
    Cimino, Guido
    Santamaria, Rita
    Guo, Yue-Wei
    Gavagnin, Margherita
    ORGANIC LETTERS, 2011, 13 (10) : 2516 - 2519
  • [42] Formation of 1,2,4-oxadiazole derivatives from Erlenmeyer azlactones and amidoximes
    Yavari, Issa
    Amirahmadi, Asiyeh
    Halvagar, Mohammad Reza
    MONATSHEFTE FUR CHEMIE, 2019, 150 (10): : 1857 - 1862
  • [43] Dualism of 1,2,4-oxadiazole ring in noncovalent interactions with carboxylic group
    Baykov, Sergey V.
    Tarasenko, Marina V.
    Semenov, Artem V.
    Katlenok, Evgeniy A.
    Shetnev, Anton A.
    Boyarskiy, Vadim P.
    JOURNAL OF MOLECULAR STRUCTURE, 2022, 1262
  • [44] Synthesis and Antibacterial Activity of Some Derivatives of 2-Methylbenzimidazole Containing 1,3,4-Oxadiazole or 1,2,4-Triazole Heterocycle
    Cong Nguyen Tien
    Duc Tran Thi Cam
    Ha Bui Manh
    Dat Nguyen Dang
    JOURNAL OF CHEMISTRY, 2016, 2016
  • [45] Novel benzodioxatriaza and dibenzodioxadiazacrown compounds carrying 1,2,4-oxadiazole moiety
    Ozer, Besra
    Durust, Yasar
    HETEROCYCLIC COMMUNICATIONS, 2022, 28 (01) : 139 - 148
  • [46] Polycyclic systems containing 1,2,4-oxadiazole ring 2. 4-(1,2,4-Oxadiazol-5-yl)pyrrolidin-2-ones: Synthesis and prediction of biological activity
    Yu. V. Kharchenko
    O. S. Detistov
    V. D. Orlov
    Chemistry of Heterocyclic Compounds, 2008, 44
  • [47] POLYCYCLIC SYSTEMS CONTAINING 1,2,4-OXADIAZOLE RING 2. 4-(1,2,4-OXADIAZOL-5-YL)PYRROLIDIN-2-ONES: SYNTHESIS AND PREDICTION OF BIOLOGICAL ACTIVITY
    Kharchenko, Yu. V.
    Detistov, O. S.
    Orlov, V. D.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (05) : 600 - 605
  • [48] Insight into the Synthesis, Biological Activity, and Structure-activity Relationship of 1,2,4-Oxadiazole and Analogs: A Comprehensive Review
    Kumar, Greesh
    Kumar, Rajnish
    Mazumder, Avijit
    Singh, Himanshu
    Kumar, Upendra
    Abdullah, Mohd. Mustaqeem
    Yar, Mohammad Shahar
    Kumar, Neeraj
    LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 21 (09) : 1437 - 1464
  • [49] Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors
    Mahmoud, Mohamed A.
    Mohammed, Anber F.
    Salem, Ola I. A.
    Almutairi, Tahani Mazyad
    Braese, Stefan
    Youssif, Bahaa G. M.
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2024, 39 (01)
  • [50] Convenient synthesis and biological profile of 5-amino-substituted 1,2,4-oxadiazole derivatives
    Ispikoudi, Maria
    Amvrazis, Michalis
    Kontogiorgis, Christos
    Koumbis, Alexandros E.
    Litinas, Konstantinos E.
    Hadjipavlou-Litina, Dimitra
    Fylaktakidou, Konstantina C.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (12) : 5635 - 5645
12345