The CRISPR/Cas9 System and the Possibility of Genomic Edition for Cardiology

被引:4
作者
Arend, Marcela Corso [1 ,2 ]
Pereira, Jessica Olivaes [1 ,3 ]
Markoski, Melissa Medeiros [1 ]
机构
[1] Fundacao Univ Cardiol IC FUC, Inst Cardiol, Programa Posgrad Ciencias Saude Cardiol, Lab Cardiol Mol & Celular, Porto Alegre, RS, Brazil
[2] Univ Vale Rio Sinos UNISINOS, Sao Leopoldo, RS, Brazil
[3] Univ Fed Ciencias Saude Porto Alegre UFCSPA, Porto Alegre, RS, Brazil
关键词
Cardiovascular Diseases / mortality; Morbidity; Risk Factors; Prevention & Control; Molecular Biology; Genomics; DISEASES;
D O I
10.5935/abc.20160200
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:81 / 83
页数:3
相关论文
共 15 条
[1]   Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing [J].
Ding, Qiurong ;
Strong, Alanna ;
Patel, Kevin M. ;
Ng, Sze-Ling ;
Gosis, Bridget S. ;
Regan, Stephanie N. ;
Cowan, Chad A. ;
Rader, Daniel J. ;
Musunuru, Kiran .
CIRCULATION RESEARCH, 2014, 115 (05) :488-+
[2]   Variations in the Prevalence of Risk Factors for Coronary Artery Disease in Rio Grande do Sul-Brazil: A Comparative Analysis between 2002 and 2014 [J].
Gus, Iseu ;
Ribeiro, Rodrigo Antonini ;
Kato, Sergio ;
Bastos, Juliano ;
Medina, Claudio ;
Zazlavsky, Claudio ;
Portal, Vera Lucia ;
Timmers, Rita ;
Markoski, Melissa Medeiros ;
Mascia Gottschall, Carlos Antonio .
ARQUIVOS BRASILEIROS DE CARDIOLOGIA, 2015, 105 (06) :573-579
[3]   Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system [J].
Jao, Li-En ;
Wente, Susan R. ;
Chen, Wenbiao .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (34) :13904-13909
[4]   VEGF gene therapy for angiogenesis in refractory angina: Phase I/II clinical trial [J].
Kalil, Renato A. K. ;
de Salles, Felipe Borsu ;
Giusti, Imarilde Ines ;
Rodrigues, Clarissa Garcia ;
Han, Sang Won ;
Sant'Anna, Roberto Tofani ;
Ludwig, Eduardo ;
Grossman, Gabriel ;
Lunardi Prates, Paulo Roberto ;
Michelin Sant'Anna, Joao Ricardo ;
Teixeira Filho, Guaracy Fernandes ;
Nardi, Nance Beyer ;
Nesralla, Ivo Abrahao .
REVISTA BRASILEIRA DE CIRURGIA CARDIOVASCULAR, 2010, 25 (03) :311-321
[5]   Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem Cells [J].
Kim, Huen Suk ;
Bernitz, Jeffrey M. ;
Lee, Dung-Fang ;
Lemischka, Ihor R. .
STEM CELLS AND DEVELOPMENT, 2014, 23 (22) :2673-2686
[6]   The Worldwide Environment of Cardiovascular Disease: Prevalence, Diagnosis, Therapy, and Policy Issues A Report From the American College of Cardiology [J].
Laslett, Lawrence J. ;
Alagona, Peter, Jr. ;
Clark, Bernard A., III ;
Drozda, Joseph P., Jr. ;
Saldivar, Frances ;
Wilson, Sean R. ;
Poe, Chris ;
Hart, Menolly .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 60 (25) :S1-S49
[7]   Gene therapy for ischemic heart disease [J].
Lavu, Madhav ;
Gundewar, Susheel ;
Lefer, David J. .
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2011, 50 (05) :742-750
[8]   Fanconi Anemia Gene Editing by the CRISPR/Cas9 System [J].
Osborn, Mark J. ;
Gabriel, Richard ;
Webber, Beau R. ;
DeFeo, Anthony P. ;
McElroy, Amber N. ;
Jarjour, Jordan ;
Starker, Colby G. ;
Wagner, John E. ;
Joung, J. Keith ;
Voytas, Daniel F. ;
von Kalle, Christof ;
Schmidt, Manfred ;
Blazar, Bruce R. ;
Tolar, Jakub .
HUMAN GENE THERAPY, 2015, 26 (02) :114-126
[9]   Exploiting CRISPR/Cas: Interference Mechanisms and Applications [J].
Richter, Hagen ;
Randau, Lennart ;
Plagens, Andre .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 14 (07) :14518-14531
[10]   CRISPR-Cas systems for editing, regulating and targeting genomes [J].
Sander, Jeffry D. ;
Joung, J. Keith .
NATURE BIOTECHNOLOGY, 2014, 32 (04) :347-355