Bioinformatic Analysis of codon usage bias in the ompC gene of Salmonella pullorum

被引:0
作者
Bao, Xiaoyu [1 ,2 ]
Xu, Guoyang [2 ]
Fan, Lei [2 ]
Liu, Minggang [2 ]
Zhou, Yao [2 ]
Pan, Kangcheng [1 ,2 ]
机构
[1] Sichuan Agr Univ, Coll Vet Med, Inst Prevent Vet Med, 46 Xinkang Rd, Yaan 625014, Sichuan, Peoples R China
[2] Sichuan Agr Univ, Key Lab Anim Dis & Human Hlth Sichuan Prov, Yaan 625014, Sichuan, Peoples R China
来源
BIOTECHNOLOGY, CHEMICAL AND MATERIALS ENGINEERING III, PTS 1 AND 2 | 2014年 / 884-885卷
关键词
codon usage bias; ompC; Salmonella pullorum; ADAPTATION INDEX; ESCHERICHIA-COLI; EXPRESSION; SELECTION; GENOME;
D O I
10.4028/www.scientific.net/AMR.884-885.394
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The aim was to identify codon usage bias between the newly comfirmed Salmonella pullorum outer membrane protein C (ompC) gene (GenBank accession No. CP003047) and that of other 21 reference Enterobacteriaceae,and we performed comparative analysis of the codon usage bias among different organisms by a series of bioinformatics softwares The apparent codon usage bias in the 22 ompC were indicated by the codon adaptation index (CAI), effective number of codons (ENc)and the value of G+C content at the 3rd codon position( GC3s).The Enc-plot revealed that these outer membrane protein C genes are subject to GC compositional constraints.The correlation analysis with other four organisms implied that codon usage pattern of E.coli is similar to Salmonella pullorum OmpC.
引用
收藏
页码:394 / +
页数:3
相关论文
共 24 条
[1]   Conformational epitope mapping of OmpC, a major cell surface antigen from Salmonella typhi [J].
Arockiasamy, A ;
Murthy, GS ;
Rukmini, MR ;
Baalaji, NS ;
Katpally, UC ;
Krishnaswamy, S .
JOURNAL OF STRUCTURAL BIOLOGY, 2004, 148 (01) :22-33
[2]   Pullorum disease and fowl typhoidnew thoughts on old diseases: a review [J].
Barrow, P. A. ;
Freitas Neto, O. C. .
AVIAN PATHOLOGY, 2011, 40 (01) :1-13
[3]   THE RELATIONSHIP BETWEEN BASE COMPOSITION AND CODON USAGE IN BACTERIAL GENES AND ITS USE FOR THE SIMPLE AND RELIABLE IDENTIFICATION OF PROTEIN-CODING SEQUENCES [J].
BIBB, MJ ;
FINDLAY, PR ;
JOHNSON, MW .
GENE, 1984, 30 (1-3) :157-166
[4]   Synonymous codon bias is related to gene length in Escherichia coli: Selection for translational accuracy? [J].
EyreWalker, A .
MOLECULAR BIOLOGY AND EVOLUTION, 1996, 13 (06) :864-872
[5]   CODON USAGE IN BACTERIA - CORRELATION WITH GENE EXPRESSIVITY [J].
GOUY, M ;
GAUTIER, C .
NUCLEIC ACIDS RESEARCH, 1982, 10 (22) :7055-7074
[6]   The relationship between synonymous codon usage and protein structure in Escherichia coli and Homo sapiens [J].
Gu, WJ ;
Zhou, T ;
Ma, JM ;
Sun, XA ;
Lu, ZH .
BIOSYSTEMS, 2004, 73 (02) :89-97
[7]   Studies on the relationships between the synonymous codon usage and protein secondary structural units [J].
Gupta, SK ;
Majumdar, S ;
Bhattacharya, TK ;
Ghosh, TC .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 269 (03) :692-696
[8]  
IKEMURA T, 1985, MOL BIOL EVOL, V2, P13
[9]   Revisiting the codon adaptation index from a whole-genome perspective: analyzing the relationship between gene expression and codon occurrence in yeast using a variety of models [J].
Jansen, R ;
Bussemaker, HJ ;
Gerstein, M .
NUCLEIC ACIDS RESEARCH, 2003, 31 (08) :2242-2251
[10]  
Jha Richa, 2012, J ISRN VET SCI