High-intensity aerobic training lowers blood pressure and modulates the renal renin-angiotensin system in spontaneously hypertensive rats

被引：5

作者：

Almeida, Jeeser Alves ^{[1
,2
]}

Motta-Santos, Daisy ^{[3
]}

Petriz, Bernardo Assis ^{[4
,5
]}

Gomes, Clarissa Pedrosa Da Costa ^{[6
]}

Nogueira, Murilo Esteves ^{[1
,2
]}

Pereira, Rinaldo Wellerson ^{[7
]}

Araujo, Ronaldo Carvalho ^{[8
]}

Prestes, Jonato ^{[9
]}

Franco, Octavio Luiz ^{[7
,9
,10
]}

机构：

[1] Univ Fed Mato Grosso do Sul, Grad Program Hlth & Dev, Pioneiros, MS, Brazil

[2] Univ Fed Mato Grosso do Sul, Grad Program Movement Sci, Res Exercise & Nutr Hlth & Sports Performance PEN, Pioneiros, MS, Brazil

[3] Univ Fed Minas Gerais, Sports Dept, Belo Horizonte, MG, Brazil

[4] Univ Franca UNIFRAN, Grad Program Hlth Promot, Franca, SP, Brazil

[5] UDF, Lab Mol Exercise Physiol, Univ Ctr, Brasilia, DF, Brazil

[6] Luxembourg Inst Hlth, Cardiovasc Res Unit, Luxembourg, Luxembourg

[7] Univ Catolica Brasilia, Grad Program Genom Sci & Biotechnol, St Name & SGAN 916 MOdulo B Ave W5 Asa Norte, BR-70790160 Brasilia, DF, Brazil

[8] Univ Fed Sao Paulo, Dept Biophys, Sao Paulo, SP, Brazil

[9] Univ Catolica Brasilia, Grad Program Phys Educ, Brasilia, DF, Brazil

[10] Catholic Univ Don Bosco, S Inova Biotech, Biotechnol Grad Program, Campo Grande, MS, Brazil

来源：

CLINICAL AND EXPERIMENTAL HYPERTENSION | 2020年 / 42卷 / 03期

关键词：

Renin-angiotensin system; high-intensity exercise; blood pressure; hypertension; CONVERTING ENZYME-2; EXERCISE; INTERLEUKIN-6; BENEFITS; RECEPTOR; MUSCLE; KIDNEY;

D O I：

10.1080/10641963.2019.1619755

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Background: This study aimed to verify the effects of high-intensity aerobic training (HIAT) on BP control and renin-angiotensin system (RAS) components in renal tissue of SHR. Ten SHRs received HIAT or control for 8-weeks. At the end of the training, the SBP showed a reduction of similar to 30mmHg (p < .01) in HIAT and increased by similar to 15 mmHg in the control group. HIAT resulted in a higher release of nitrite, IL-6, ACE2 and ATR2. These results indicated an association between BP, NO and renal RAS.

引用

页码：233 / 238

页数：6

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