Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States

被引:78
作者
Apperley, Jane [1 ]
Niederwieser, Dietger [2 ]
Huang, Xiao-jun [3 ]
Nagler, Arnon [4 ,5 ]
Fuchs, Ephraim [6 ]
Szer, Jeff [7 ,8 ]
Kodera, Yoshihisa [9 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Dept Haematol, London, England
[2] Univ Leipzig, Div Hematol & Med Oncol, D-04109 Leipzig, Germany
[3] Peking Univ, Peoples Hosp, Beijing Key Lab HSCT, Inst Hematol, Beijing 100871, Peoples R China
[4] Chaim Sheba Med Ctr, Div Hematol, BMT, IL-52621 Tel Hashomer, Israel
[5] Chaim Sheba Med Ctr, Cord Blood Bank, IL-52621 Tel Hashomer, Israel
[6] Johns Hopkins Univ, Blood & Bone Marrow Canc Program, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA
[7] Royal Melbourne Hosp, Dept Clin Haematol, Melbourne, Vic, Australia
[8] Royal Melbourne Hosp, BMT Serv, Melbourne, Vic, Australia
[9] Aichi Med Univ, Sch Med, Dept Promot Blood & Marrow Transplantat, Nagakute, Aichi 4801195, Japan
关键词
Global Activity Survey; Haplo-transplantation; Haplo-HSCT; Beijing Protocol; Europe; United States; BONE-MARROW TRANSPLANTS; HLA-IDENTICAL SIBLINGS; POSTTRANSPLANTATION CYCLOPHOSPHAMIDE; ACUTE-LEUKEMIA; CORD BLOOD; DONORS; SURVIVAL; DISEASE; MALIGNANCIES; ENGRAFTMENT;
D O I
10.1016/j.bbmt.2015.11.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
One of the major projects of the Worldwide Network for Blood and Marrow Transplantation (WBMT) is to promote hematopoietic stem cell transplantation (HSCT) in emerging countries in the world. For these countries, HLA haploidentical HSCT (haplo-HSCT) from family members is an attractive approach because of its cost effectiveness. To learn the current status, including recent trends, of haplo-HSCT, the WBMT invited speakers from major transplant centers in 3 regions (Asia, Europe, and North America) to present at its annual WBMT Joint Session. This article represents the direct reports from these 3 speakers in addition to introductions by 2 WBMT speakers who address data from the Global Transplant Activity survey. It must be emphasized, however, that certain promising results of haplo-HSCT presented in this article were obtained at well-experienced institutes. (C) 2016 American Society for Blood and Marrow Transplantation.
引用
收藏
页码:23 / 26
页数:4
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