Future applications of mass spectrometry in microbiology

被引：3

作者：

Vila, Jordi ^{[1
]}

Zboromyrska, Yuliya ^{[1
]}

Burillo, Almudena ^{[2
]}

Bouza, Emilio ^{[2
]}

机构：

[1] Univ Barcelona, Fac Med, Ctr Recerca Salut Int Barcelona CRESIB, Microbiol Serv,Hosp Clin,Inst Salud Global Barcel, Barcelona, Spain

[2] Univ Complutense Madrid, Fac Med,CIBER Enfermedades Resp CIBERES CB06 06 0, Serv Microbiol Clin & Enfermedades Infecciosas, Hosp Gen Univ Gregorio Maranon,Inst Invest Sanita, Madrid, Spain

来源：

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2016年 / 34卷

关键词：

Mass spectrometry; MALDI-TOF; Clinical samples; Toxins; Antigens; Virology; Parasitology;

D O I：

10.1016/S0213-005X(16)30192-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry (MS) has been vigorously introduced in many clinical microbiology laboratories for the rapid and accurate identification of bacteria and fungi. In fact, the implementation of this methodology can be considered a revolution in these laboratories. In addition to microbial identification, MALDI-TOF MS is being used for the detection of some mechanisms of antibiotic resistance and for the molecular typing of bacteria. A number of current and future applications that increase the versatility of this methodology may also be mentioned. Among these are its direct application on clinical samples, the detection of toxins or specific microbial antigens, and its application in the fields of virology and parasitology. (C) 2016 Elsevier Espafia, S.L.U. All rights reserved.

引用

页码：53 / 58

页数：6

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