Endoplasmic reticulum stress and angiogenesis: is there an interaction between them?

被引：23

作者：

Paridaens, Annelies ^{[1
]}

Laukens, Debby ^{[1
]}

Vandewynckel, Yves-Paul ^{[1
]}

Coulon, Stephanie ^{[1
]}

Van Vlierberghe, Hans ^{[1
]}

Geerts, Anja ^{[1
]}

Colle, Isabelle ^{[1
]}

机构：

[1] Univ Ghent, Dept Gastroenterol & Hepatol, B-9000 Ghent, Belgium

来源：

LIVER INTERNATIONAL | 2014年 / 34卷 / 06期

关键词：

angiogenesis; cirrhosis; endoplasmic reticulum stress; liver diseases; unfolded protein response; vascular endothelial growth factor A; ENDOTHELIAL GROWTH-FACTOR; UNFOLDED PROTEIN RESPONSE; ER STRESS; OXIDIZED PHOSPHOLIPIDS; DEPENDENT REGULATION; CELL-SURVIVAL; LIVER-DISEASE; VEGF; ACTIVATION; EXPRESSION;

D O I：

10.1111/liv.12457

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

When cells are subjected to stress by changes in their extracellular environment, unfolded proteins accumulate in the endoplasmic reticulum (ER), causing ER stress. This initiates the unfolded protein response (UPR), a signal transduction cascade aiming at restoring cellular homeostasis. The UPR and angiogenesis are involved in the pathogenesis of many diseases such as cancer, pulmonary diseases and chronic liver diseases (CLDs) including alcoholic liver disease, non-alcoholic steatohepatitis and hepatitis B. This review summarizes the upcoming knowledge of the interaction between the UPR and angiogenesis in physiological angiogenesis and in different CLDs and other diseases.

引用

页码：E10 / E18

页数：9

共 75 条

[1]

Abcouwer SF, 2002, INVEST OPHTH VIS SCI, V43, P2791

[2] Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways [J].

Afonyushkin, Taras ;

Oskolkova, Olga V. ;

Philippova, Maria ;

Resink, Therese J. ;

Erne, Paul ;

Binder, Bernd R. ;

Bochkov, Valery N. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2010, 30 (05) :1007-U275

[3] In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C [J].

Asselah, Tarik ;

Bieche, Ivan ;

Mansouri, Abdellah ;

Laurendeau, Ingrid ;

Cazals-Hatem, Dominique ;

Feldmann, Gerard ;

Bedossa, Pierre ;

Paradis, Valerie ;

Martinot-Peignoux, Michelle ;

Lebrec, Didier ;

Guichard, Cecile ;

Ogier-Denis, Eric ;

Vidaud, Michel ;

Tellier, Zera ;

Soumelis, Vassili ;

Marcellin, Patrick ;

Moreau, Richard .

JOURNAL OF PATHOLOGY, 2010, 221 (03) :264-274

[4] Inositol-requiring enzyme 1α is a key regulator of angiogenesis and invasion in malignant glioma [J].

Auf, Gregor ;

Jabouille, Arnaud ;

Guerit, Sylvaine ;

Pineau, Raphael ;

Delugin, Maylis ;

Bouchecareilh, Marion ;

Magnin, Noel ;

Favereaux, Alexandre ;

Maitre, Marlene ;

Gaiser, Timo ;

von Deimling, Andreas ;

Czabanka, Marcus ;

Vajkoczy, Peter ;

Chevet, Eric ;

Bikfalvi, Andreas ;

Moenner, Michel .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (35) :15553-15558

[5] Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response [J].

Bertolotti, A ;

Zhang, YH ;

Hendershot, LM ;

Harding, HP ;

Ron, D .

NATURE CELL BIOLOGY, 2000, 2 (06) :326-332

[6] PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation [J].

Bobrovnikova-Marjon, Ekaterina ;

Hatzivassiliou, Georgia ;

Grigoriadou, Christina ;

Romero, Margarita ;

Cavener, Douglas R. ;

Thompson, Craig B. ;

Diehl, J. Alan .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (42) :16314-16319

[7] Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability:: Role of nuclear Factor-κB and activating protein-1 [J].

Bobrovnikova-Marjon, EV ;

Marjon, PL ;

Barbash, O ;

Jagt, DLV ;

Abcouwer, SF .

CANCER RESEARCH, 2004, 64 (14) :4858-4869

[8] The Unfolded Protein Response Regulates an Angiogenic Response by the Kidney Epithelium during Ischemic Stress [J].

Bouvier, Nicolas ;

Fougeray, Sophie ;

Beaune, Philippe ;

Thervet, Eric ;

Pallet, Nicolas .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (18) :14557-14568

[9] Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions [J].

Carmeliet, P ;

Moons, L ;

Luttun, A ;

Vincenti, V ;

Compernolle, V ;

De Mol, M ;

Wu, Y ;

Bon, F ;

Devy, L ;

Beck, H ;

Scholz, D ;

Acker, T ;

DiPalma, T ;

Dewerchin, M ;

Noel, A ;

Stalmans, I ;

Barra, A ;

Blacher, S ;

Vandendriessche, T ;

Ponten, A ;

Eriksson, U ;

Plate, KH ;

Foidart, JM ;

Schaper, W ;

Charnock-Jones, DS ;

Hicklin, DJ ;

Herbert, JM ;

Collen, D ;

Persico, MG .

NATURE MEDICINE, 2001, 7 (05) :575-583

[10] Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele [J].

Carmeliet, P ;

Ferreira, V ;

Breier, G ;

Pollefeyt, S ;

Kieckens, L ;

Gertsenstein, M ;

Fahrig, M ;

Vandenhoeck, A ;

Harpal, K ;

Eberhardt, C ;

Declercq, C ;

Pawling, J ;

Moons, L ;

Collen, D ;

Risau, W ;

Nagy, A .

NATURE, 1996, 380 (6573) :435-439

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