(E)-3-[4-(Pentyloxy)phenyl]-1-phenylprop-2-en-1-one

被引：2

作者：

Abbas, Asghar ^{[2
]}

Rauf, M. Khawar ^{[2
]}

Bolte, Michael ^{[1
]}

Hasan, Aurangzeb ^{[2
]}

机构：

[1] Goethe Univ Frankfurt, Inst Anorgan Chem, D-60438 Frankfurt, Germany

[2] Quaid I Azam Univ Islamabad, Dept Chem, Islamabad 45320, Pakistan

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷

关键词：

ANTICANCER ACTIVITY; CHALCONES;

D O I：

10.1107/S1600536809016754

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C20H22O2, crystallizes with two independent molecules in the asymmetric unit. In each molecule, all the non-H atoms lie in a common plane (r.m.s. deviations of 0.098 and 0.079 angstrom). There is a pi-pi stacking interaction in the crystal structure. The central aromatic rings of the two molecules, which are stacked head-to-tail one above the other, are separated by centroid-to-centroid distances of 3.872 (13) and 3.999 (10) angstrom.

引用

页码：O1280 / U1884

页数：14

共 13 条

[1] A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome [J].

Achanta, Geetha ;

Modzelewska, Aneta ;

Feng, Li ;

Khan, Saeed R. ;

Huang, Peng .

MOLECULAR PHARMACOLOGY, 2006, 70 (01) :426-433

[2] TABLES OF BOND LENGTHS DETERMINED BY X-RAY AND NEUTRON-DIFFRACTION .1. BOND LENGTHS IN ORGANIC-COMPOUNDS [J].

ALLEN, FH ;

KENNARD, O ;

WATSON, DG ;

BRAMMER, L ;

ORPEN, AG ;

TAYLOR, R .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1987, (12) :S1-S19

[3] 2-Bromo-1-chlorophenyl-3-(4-methoxyphenyl)prop-2-en-1-one [J].

Harrison, WTA ;

Yathirajan, HS ;

Sarojini, BK ;

Narayana, B ;

Raj, KKV .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2006, 62 :O1578-O1579

[4] 3-(4-Bromophenyl)-1-(4-nitrophenyl)-prop-2-en-1-one [J].

Rosli, MM ;

Patil, PS ;

Fun, HK ;

Razak, IA ;

Dharmaprakash, SM .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 :O1466-O1468

[5]

Sarissky M, 2008, NEURO-ONCOLOGY, V10, P1112

[6] A short history of SHELX [J].

Sheldrick, George M. .

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 :112-122

[7] Oxygenated chalcones and bischalcones as a new class of inhibitors of DNA topoisomerase II of malarial parasites [J].

Srivastava, Shalini ;

Joshi, Shweta ;

Singh, Alok R. ;

Yadav, Sarika ;

Saxena, A. S. ;

Ram, V. J. ;

Chandra, Subhash ;

Saxena, J. K. .

MEDICINAL CHEMISTRY RESEARCH, 2008, 17 (2-7) :234-244

[8]

Stoe & Cie, 2001, X AREA

[9] Effects of the Kava Chalcone Flavokawain A Differ in Bladder Cancer Cells with Wild-type versus Mutant p53 [J].

Tang, Yaxiong ;

Simoneau, Anne R. ;

Xie, Jun ;

Shahandeh, Babbak ;

Zi, Xiaolin .

CANCER PREVENTION RESEARCH, 2008, 1 (06) :439-451

[10] Inhibitory activity of prostaglandin E2 production by the synthetic 2′-hydroxychalcone analogues: Synthesis and SAR study [J].

Thanh-Dao Tran ;

Park, Haeil ;

Kim, Hyun Pyo ;

Ecker, Gerhard F. ;

Khac-Minh Thai .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (06) :1650-1653

← 1 2 →