Theoretical study and simulation of light-addressable potentiometric sensors

被引：20

作者：

Guo, Yuanyuan ^{[1
]}

Miyamoto, Ko-ichiro ^{[1
]}

Wagner, Torsten ^{[2
]}

Schoening, Michael J. ^{[2
]}

Yoshinobu, Tatsuo ^{[1
,3
]}

机构：

[1] Tohoku Univ, Dept Elect Engn, Aoba Ku, Sendai, Miyagi 9808577, Japan

[2] Aachen Univ Appl Sci, INB, D-52428 Julich, Germany

[3] Tohoku Univ, Dept Biomed Engn, Aoba Ku, Sendai, Miyagi 9808577, Japan

来源：

PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE | 2014年 / 211卷 / 06期

基金：

日本学术振兴会;

关键词：

biosensors; device simulations; light-addressable potentiometric sensors; IMAGING SENSOR; LAPS; MICROPHYSIOMETER; TECHNOLOGY; DESIGN;

D O I：

10.1002/pssa.201330354

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance. Distribution of minority carriers inside a Si-based LAPS structure under illumination with different wavelengths. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：1467 / 1472

页数：6

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