The evidence for high flow nasal cannula devices in infants

被引：24

作者：

Haq, Iram ^{[1
]}

Gopalakaje, Saikiran ^{[1
,2
]}

Fenton, Alan C. ^{[2
]}

McKean, Michael C. ^{[1
]}

O'Brien, Christopher J. ^{[1
]}

Brodlie, Malcolm ^{[1
,3
]}

机构：

[1] Great North Childrens Hosp, Dept Paediat Resp Med, Newcastle Upon Tyne, Tyne & Wear, England

[2] Royal Victoria Infirm, Newcastle Neonatal Serv, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England

[3] Newcastle Univ, Inst Cellular Med, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

PAEDIATRIC RESPIRATORY REVIEWS | 2014年 / 15卷 / 02期

基金：

英国医学研究理事会;

关键词：

High flow nasal cannula; Bronchiolitis; Neonate; Respiratory distress syndrome; Infant; Continuous positive airway pressure; Non-invasive ventilation; POSITIVE AIRWAY PRESSURE; VIRAL BRONCHIOLITIS; OXYGEN; CPAP; THERAPY; NURSERIES; VOLUME;

D O I：

10.1016/j.prrv.2013.12.002

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

High flow nasal cannula (HFNC) devices deliver an adjustable mixture of heated and humidified oxygen and air at a variable flow rate. Over recent years HFNC devices have become a frequently used method of non-invasive respiratory support in infants and preterm neonates that is generally popular amongst clinicians and nursing staff due to ease of use and being well tolerated by patients. Despite this rapid adoption relatively little is known about the exact mechanisms of action of HFNC however and only recently have data from randomised controlled trials started to become available. We describe the features of a modern HFNC device and discuss current knowledge about the mechanisms of action and results of clinical studies in preterm neonates and infants with bronchiolitis. We also highlight future areas of research that are likely to increase our understanding, inform best clinical practice and strengthen the evidence base for the use of HFNC. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：124 / 134

页数：11

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