The evidence for high flow nasal cannula devices in infants

被引:25
作者
Haq, Iram [1 ]
Gopalakaje, Saikiran [1 ,2 ]
Fenton, Alan C. [2 ]
McKean, Michael C. [1 ]
O'Brien, Christopher J. [1 ]
Brodlie, Malcolm [1 ,3 ]
机构
[1] Great North Childrens Hosp, Dept Paediat Resp Med, Newcastle Upon Tyne, Tyne & Wear, England
[2] Royal Victoria Infirm, Newcastle Neonatal Serv, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
[3] Newcastle Univ, Inst Cellular Med, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
基金
英国医学研究理事会;
关键词
High flow nasal cannula; Bronchiolitis; Neonate; Respiratory distress syndrome; Infant; Continuous positive airway pressure; Non-invasive ventilation; POSITIVE AIRWAY PRESSURE; VIRAL BRONCHIOLITIS; OXYGEN; CPAP; THERAPY; NURSERIES; VOLUME;
D O I
10.1016/j.prrv.2013.12.002
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
High flow nasal cannula (HFNC) devices deliver an adjustable mixture of heated and humidified oxygen and air at a variable flow rate. Over recent years HFNC devices have become a frequently used method of non-invasive respiratory support in infants and preterm neonates that is generally popular amongst clinicians and nursing staff due to ease of use and being well tolerated by patients. Despite this rapid adoption relatively little is known about the exact mechanisms of action of HFNC however and only recently have data from randomised controlled trials started to become available. We describe the features of a modern HFNC device and discuss current knowledge about the mechanisms of action and results of clinical studies in preterm neonates and infants with bronchiolitis. We also highlight future areas of research that are likely to increase our understanding, inform best clinical practice and strengthen the evidence base for the use of HFNC. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:124 / 134
页数:11
相关论文
共 44 条
  • [1] Predictors of failure in infants with viral bronchiolitis treated with high-flow, high-humidity nasal cannula therapy
    Abboud, Patricia A.
    Roth, Patrick J.
    Skiles, Cheryl L.
    Stolfi, Adrienne
    Rowin, Mark E.
    [J]. PEDIATRIC CRITICAL CARE MEDICINE, 2012, 13 (06) : E343 - E349
  • [2] Early weaning from CPAP to high flow nasal cannula in preterm infants is associated with prolonged oxygen requirement: A randomized controlled trial
    Abdel-Hady, Hesham
    Shouman, Basma
    Aly, Hany
    [J]. EARLY HUMAN DEVELOPMENT, 2011, 87 (03) : 205 - 208
  • [3] Nasopharyngeal Airway Pressures in Bronchiolitis Patients Treated With High-Flow Nasal Cannula Oxygen Therapy
    Arora, Bhawana
    Mahajan, Prashant
    Zidan, Marwan A.
    Sethuraman, Usha
    [J]. PEDIATRIC EMERGENCY CARE, 2012, 28 (11) : 1179 - 1184
  • [4] Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for preterm infants
    Campbell, D. M.
    Shah, P. S.
    Shah, V.
    Kelly, E. N.
    [J]. JOURNAL OF PERINATOLOGY, 2006, 26 (09) : 546 - 549
  • [5] Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients
    Corley, A.
    Caruana, L. R.
    Barnett, A. G.
    Tronstad, O.
    Fraser, J. F.
    [J]. BRITISH JOURNAL OF ANAESTHESIA, 2011, 107 (06) : 998 - 1004
  • [6] Comparing two methods of delivering high-flow gas therapy by nasal cannula following endotracheal extubation: a prospective, randomized, masked, crossover trial
    D Woodhead, D.
    Lambert, D. K.
    Clark, J. M.
    Christensen, R. D.
    [J]. JOURNAL OF PERINATOLOGY, 2006, 26 (08) : 481 - 485
  • [7] De Paoli AG, 2008, COCHRANE DB SYST REV, V1, DOI DOI 10.1002/14651858.CD002977.PUB2
  • [8] Deakins KM, 2009, RESP CARE, V54, P1252
  • [9] Research in high flow therapy: Mechanisms of action
    Dysart, Kevin
    Miller, Thomas L.
    Wolfson, Maria R.
    Shaffer, Thomas H.
    [J]. RESPIRATORY MEDICINE, 2009, 103 (10) : 1400 - 1405
  • [10] High-Flow Nasal Cannula: A Kinder, Gender CPAP?
    Finer, Neil N.
    Mannino, Frank L.
    [J]. JOURNAL OF PEDIATRICS, 2009, 154 (02) : 160 - 162