Carbon Nanotubes: Synthesis, Properties and Pharmaceutical Applications

被引：44
|
作者：
Singh, Inderbir [1 ]
Rehni, Ashish K. [1 ]
Kumar, Pradeep [1 ]
Kumar, Manoj [1 ]
Aboul-Enein, Hassan Y. [1 ]
机构：
[1] Natl Res Ctr, Pharmaceut & Med Chem Dept, Cairo 12311, Egypt
来源：
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES | 2009年 / 17卷 / 04期
关键词：
Applications; Carbon nanotubes; Properties; Synthesis; Toxicology; DRUG-DELIVERY; PULMONARY TOXICITY; DNA; CELLS; FUNCTIONALIZATION; CYTOTOXICITY; PARTICLES; FULLERENE; PEPTIDES; BINDING;
D O I：
10.1080/15363830903008018
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Carbon nanotubes (CNTs) are unique cylindrical forms of carbon that have carved a niche in the field of nanomedicine. The possibility of incorporating functionalized carbon nanotubes into cells and the biological milieu offers numerous advantages for potential applications in biology, pharmacology and drug delivery. One of the most promising is the utilization of CNTs as a new carrier system for the delivery of therapeutic molecules. Furthermore, recent findings of improved cell membrane permeability for carbon nanotubes would expand medical applications to therapeutics using carbon nanotubes as carriers in gene delivery systems. This review discusses the synthetic methods, properties and potential pharmaceutical application of CNTs. Toxicological considerations of CNTs have also been delineated.
引用
收藏
页码：361 / 377
页数：17
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