An Asian patient with intraocular lymphoma treated by intravitreal methotrexate

被引：21
|
作者：
Wang, Jia-Kang
Yang, Chung-May
Lin, Chang-Ping
Shan, Yin-Dong
Lo, Andy Y.
Tien, Hwei-Fang
机构：
[1] Natl Taiwan Univ Hosp, Dept Ophthalmol, Taipei 100, Taiwan
[2] Far Eastern Mem Hosp, Dept Ophthalmol, Taipei, Taiwan
[3] Natl Taiwan Univ, Dept Internal Med, Taipei 10764, Taiwan
来源：
JAPANESE JOURNAL OF OPHTHALMOLOGY | 2006年 / 50卷 / 05期
关键词：
chemotherapy; intraocular lymphoma; intravitreal injection; methotrexate; primary central nervous system lymphoma;
D O I：
10.1007/s10384-005-0327-4
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Background: To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma. Case: A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma. Observations: The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up. Conclusion: Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma.
引用
收藏
页码：474 / 478
页数：5
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