An Asian patient with intraocular lymphoma treated by intravitreal methotrexate

被引：21
|
作者：
Wang, Jia-Kang
Yang, Chung-May
Lin, Chang-Ping
Shan, Yin-Dong
Lo, Andy Y.
Tien, Hwei-Fang
机构：
[1] Natl Taiwan Univ Hosp, Dept Ophthalmol, Taipei 100, Taiwan
[2] Far Eastern Mem Hosp, Dept Ophthalmol, Taipei, Taiwan
[3] Natl Taiwan Univ, Dept Internal Med, Taipei 10764, Taiwan
来源：
JAPANESE JOURNAL OF OPHTHALMOLOGY | 2006年 / 50卷 / 05期
关键词：
chemotherapy; intraocular lymphoma; intravitreal injection; methotrexate; primary central nervous system lymphoma;
D O I：
10.1007/s10384-005-0327-4
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Background: To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma. Case: A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma. Observations: The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up. Conclusion: Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma.
引用
收藏
页码：474 / 478
页数：5
相关论文
共 50 条
  • [21] Repeated IL-10 measurement in aqueous humor and OCT imaging are valuable tools to monitor intraocular lymphoma treated with intravitreal injections of methotrexate
    Saleh, Maher
    Nikolitch, Katerina
    Bourcier, Tristan
    Speeg, Claude
    Gaucher, David
    GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2012, 250 (05) : 761 - 764
  • [22] Development of Chitosan and Polylactic Acid Based Methotrexate Intravitreal Micro-Implants to Treat Primary Intraocular Lymphoma: An In Vitro Study
    Manna, Soumyarwit
    Augsburger, James J.
    Correa, Zelia M.
    Landero, Julio A.
    Banerjee, Rupak K.
    JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 2014, 136 (02):
  • [23] Clinical outcomes following intravitreal methotrexate for primary vitreoretinal lymphoma
    Anthony, Casey L.
    Bavinger, J. Clay
    Shantha, Jessica G.
    O'Keefe, Ghazala D.
    Pearce, William A.
    Voloschin, Alfredo
    Grossniklaus, Hans E.
    Yeh, Steven
    INTERNATIONAL JOURNAL OF RETINA AND VITREOUS, 2021, 7 (01)
  • [24] Clinical outcomes following intravitreal methotrexate for primary vitreoretinal lymphoma
    Casey L. Anthony
    J. Clay Bavinger
    Jessica G. Shantha
    Ghazala D. O’Keefe
    William A. Pearce
    Alfredo Voloschin
    Hans E. Grossniklaus
    Steven Yeh
    International Journal of Retina and Vitreous, 7
  • [25] Reduced frequency of Intravitreal methotrexate injection lowers the risk of Keratopathy in Vitreoretinal lymphoma patients
    Zhou, Xian
    Zhou, Xianjin
    Shi, Huimin
    Lai, Jie
    Wang, Qingping
    Li, Yi
    Chen, Kun
    Li, Qingjian
    Zhou, Qiang
    Cao, Xia
    Chen, Bobin
    Xiao, Jianjiang
    BMC OPHTHALMOLOGY, 2020, 20 (01)
  • [26] Composite Cutaneous Lymphoma in a Patient With Rheumatoid Arthritis Treated With Methotrexate
    Huwait, Hassan
    Wang, Beatrice
    Shustik, Chaim
    Michel, Rene P.
    AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2010, 32 (01) : 65 - 70
  • [27] Use of intravitreal rituximab and methotrexate in vitreoretinal lymphoma
    Rahhal-Ortuno, Miriam
    Udaondo-Mirete, Patricia
    Samir Fernandez-Santodomingo, Alex
    Diaz-Llopis, Manuel
    EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2022, 32 (01) : NP199 - NP202
  • [28] Intravitreal Methotrexate
    Abdi, Fatemeh
    Mohammadi, S. Saeed
    Falavarjani, Khalil Ghasemi
    JOURNAL OF OPHTHALMIC & VISION RESEARCH, 2021, 16 (04) : 657 - 669
  • [29] Case report: Intravitreal methotrexate in intraocular acute lymphoblastic leukemia
    Pederzolli, Matteo
    Giglio, Fabio
    Cicinelli, Maria Vittoria
    Marchese, Alessandro
    Modorati, Giulio
    Mastaglio, Sara
    Ciceri, Fabio
    Bandello, Francesco
    Miserocchi, Elisabetta
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [30] Lymphoma revealed by femoral fracture in a rheumatoid arthritis patient treated with methotrexate
    J. R. Hannequin
    J. Bohly
    F. Campos
    F. Oberling
    European Journal of Orthopaedic Surgery & Traumatology, 1998, 8 (1) : 53 - 56
12345