An Asian patient with intraocular lymphoma treated by intravitreal methotrexate

被引：21
|
作者：
Wang, Jia-Kang
Yang, Chung-May
Lin, Chang-Ping
Shan, Yin-Dong
Lo, Andy Y.
Tien, Hwei-Fang
机构：
[1] Natl Taiwan Univ Hosp, Dept Ophthalmol, Taipei 100, Taiwan
[2] Far Eastern Mem Hosp, Dept Ophthalmol, Taipei, Taiwan
[3] Natl Taiwan Univ, Dept Internal Med, Taipei 10764, Taiwan
来源：
JAPANESE JOURNAL OF OPHTHALMOLOGY | 2006年 / 50卷 / 05期
关键词：
chemotherapy; intraocular lymphoma; intravitreal injection; methotrexate; primary central nervous system lymphoma;
D O I：
10.1007/s10384-005-0327-4
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Background: To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma. Case: A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma. Observations: The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up. Conclusion: Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma.
引用
收藏
页码：474 / 478
页数：5
相关论文
共 50 条
  • [1] An Asian Patient with Intraocular Lymphoma Treated by Intravitreal Methotrexate
    Jia-Kang Wang
    Chung-May Yang
    Chang-Ping Lin
    Yin-Dong Shan
    Andy Y. Lo
    Hwei-Fang Tien
    Japanese Journal of Ophthalmology, 2006, 50 : 474 - 478
  • [2] Intravitreal methotrexate resistance in a patient with primary Intraocular lymphoma
    Sen, H. Nida
    Chan, Chi-Chao
    Byrnes, Gordon
    Fariss, Robert N.
    Nussenblatt, Robert B.
    Buggage, Ronald R.
    OCULAR IMMUNOLOGY AND INFLAMMATION, 2008, 16 (1-2) : 29 - 33
  • [3] Treatment of primary intraocular lymphoma with intravitreal methotrexate
    Sou, Reika
    Ohguro, Nobuyuki
    Maeda, Tetsuo
    Saishin, Yoshitsugu
    Tano, Yasuo
    JAPANESE JOURNAL OF OPHTHALMOLOGY, 2008, 52 (03) : 167 - 174
  • [4] Treatment of primary intraocular lymphoma with intravitreal methotrexate
    Reika Sou
    Nobuyuki Ohguro
    Tetsuo Maeda
    Yoshitsugu Saishin
    Yasuo Tano
    Japanese Journal of Ophthalmology, 2008, 52 : 167 - 174
  • [5] Clinical outcomes of intravitreal methotrexate injection protocol with a reduced initial frequency for intraocular lymphoma
    Hsu, Chiung-Ju
    Hou, Hsin-An
    Lin, Chang-Ping
    Lee, Yi-Jui
    Hsu, Wen-Fang
    Yeh, Po-Ting
    JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2022, 121 (01) : 416 - 424
  • [6] Clinical outcomes of primary intraocular lymphoma patients treated with front-line systemic high-dose methotrexate and intravitreal methotrexate injection
    Ma, Wei-Li
    Hou, Hsin-An
    Hsu, Ya-Jui
    Chen, Yin-Kai
    Tang, Jih-Luh
    Tsay, Woei
    Yeh, Po-Ting
    Yang, Chung-May
    Lin, Chang-Ping
    Tien, Hwei-Fang
    ANNALS OF HEMATOLOGY, 2016, 95 (04) : 593 - 601
  • [7] Intravitreal methotrexate injections for intraocular involvement in primary central nervous system lymphoma
    Tourville, E
    Tardif, Y
    CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE, 2003, 38 (07): : 598 - 601
  • [8] High-dose methotrexate following intravitreal methotrexate administration in preventing central nervous system involvement of primary intraocular lymphoma
    Akiyama, Hiroki
    Takase, Hiroshi
    Kubo, Fumito
    Miki, Tohru
    Yamamoto, Masahide
    Tomita, Makoto
    Mochizuki, Manabu
    Miura, Osamu
    Arai, Ayako
    CANCER SCIENCE, 2016, 107 (10) : 1458 - 1464
  • [9] Therapeutic Effects of Intravitreal Methotrexate Injection for Intraocular Lymphoma Diagnosed Using Immunocytochemical Staining
    Na, Yong Jin
    Kwon, Kun Young
    Kim, Kook Young
    Chang, Young Suk
    Kim, Jung Tae
    JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, 2025, 66 (02): : 101 - 113
  • [10] Outcomes of intravitreal methotrexate to salvage eyes with relapsed primary intraocular lymphoma
    Mohammad, Mona
    Andrews, Richard M.
    Plowman, P. Nicholas
    Hay, Gordon
    Arora, Amit K.
    Cohen, Victoria M. L.
    Sagoo, Mandeep S.
    BRITISH JOURNAL OF OPHTHALMOLOGY, 2022, 106 (01) : 135 - 140
12345