High prevalence of hepatitis E virus antibodies among blood donors in Southern Brazil

被引:37
作者
Passos-Castilho, Ana Maria [1 ]
de Sena, Anne [1 ,2 ]
Geraldo, Alexandre [3 ,4 ]
Spada, Celso [4 ]
Granato, Celso F. H. [1 ,2 ]
机构
[1] Univ Fed Sao Paulo, Div Infect Dis, 781 Pedro Toledo St, BR-04039032 Sao Paulo, Brazil
[2] Fleury SA Grp, Sao Paulo, Brazil
[3] HEMOSC Santa Catarina Hematol & Hemotherapy Ctr, Blumenau, Brazil
[4] Univ Fed Santa Catarina, Dept Clin Anal, Florianopolis, SC, Brazil
基金
巴西圣保罗研究基金会;
关键词
hepatitis E virus; blood donors; seroprevalence; Brazil; TIME RT-PCR; INFECTION; SEROPREVALENCE; COUNTRIES; ASSAY;
D O I
10.1002/jmv.24336
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Brazil has been classified as moderately endemic for hepatitis E virus (HEV) infection. However, data on the seroprevalence of HEV in this region are limited. This study evaluated the prevalence of past or present HEV infection among blood donors in the metropolitan area of Itajai Valley, Southern Brazil, a region of predominant German heritage, where cultural habits result in a high consumption of pork. Serum samples from 300 blood donors were tested in December 2014 using serological and molecular methods. Anti-HEV IgG antibodies were detected in 30 (10%) subjects, and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Only one subject had anti-HEV IgM, whereas none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG in blood donors than previously reported in Brazil. (c) 2015 Wiley Periodicals, Inc.
引用
收藏
页码:361 / 364
页数:4
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