Factors affecting production of beta-carotene from Dunaliella salina microalgae

被引:87
作者
Pourkarimi, Sara [1 ]
Hallajisani, Ahmad [2 ]
Alizadehdakhel, Asghar [1 ]
Nouralishahi, Amideddin [2 ]
Golzary, Abooali [3 ]
机构
[1] Islamic Azad Univ, Rasht Branch, Dept Chem & Chem Engn, Rasht, Iran
[2] Univ Tehran, Sch Engn, Caspian Fac Engn, Biofuel Lab, Rezvanshahr Of Gilan, Iran
[3] Univ Tehran, Coll Engn, Sch Environm, POB 14155-6135, Tehran, Iran
关键词
Beta-carotene; Dunaliella salina; Extraction; Microalgae; Optimal condition; MOLECULAR-BIOLOGY; LOW-TEMPERATURE; ALGA; EXTRACTION; GROWTH; CHLOROPHYTA; EXPRESSION; STRAINS; GENE; PHOTOBIOREACTOR;
D O I
10.1016/j.bcab.2020.101771
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Dunaliella Salina is a carotene-producing microalgae well-known for its superb ability to accumulate valuable beta-carotene. The factors affecting the bio-beta-carotene production from Dunaliella salina microalgae have been investigated in this study. First, the different usages of Dunaliella salina, especially for the production of beta carotene, are described. Then, the factors affecting the process of obtaining beta-carotene from Dunaliella salina in the culture system, culture conditions, and downstream processes are investigated. Investigations show that application of airborne photo-bioreactor culture system improves the mechanism of production. It was found that among the culture conditions, the parameters such as ambient salinity, temperature, and intensity of illumination are the most effective ones. The optimal values for these parameters, the highest cellular density of Dunaliella salina and the highest beta-carotene production are determined. The extraction step is known as the most critical step in the downstream processes of beta-carotene production.
引用
收藏
页数:14
相关论文
共 97 条
[11]  
Borowitzka L.J., 1989, Algal and Cyanobacterial Biotechnology, P294
[12]   The taxonomy of the genus Dunaliella (Chlorophyta, Dunaliellales) with emphasis on the marine and halophilic species [J].
Borowitzka, Michael A. ;
Siva, Christopher J. .
JOURNAL OF APPLIED PHYCOLOGY, 2007, 19 (05) :567-590
[13]   Biofuels from microalgae-A review of technologies for production, processing, and extractions of biofuels and co-products [J].
Brennan, Liam ;
Owende, Philip .
RENEWABLE & SUSTAINABLE ENERGY REVIEWS, 2010, 14 (02) :557-577
[14]  
Challem JJ., 1997, J ORTHOMOL MED, V12, P11
[15]   Expression of Synthetic Phytoene Synthase Gene to Enhance β-Carotene Production in Scenedesmus sp CPC2 [J].
Chen, Chun-Yen ;
Kao, Ai-Ling ;
Tsai, Zheng-Chia ;
Shen, Yu-Mei ;
Kao, Pei-Hsun ;
Ng, I-Son ;
Chang, Jo-Shu .
BIOTECHNOLOGY JOURNAL, 2017, 12 (11)
[16]   Effects of Salinity Changes on the Growth of Dunaliella salina and Its Isozyme Activities of Glycerol-3-phosphate Dehydrogenase [J].
Chen, Hui ;
Jiang, Jian-Guo ;
Wu, Guang-Hong .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (14) :6178-6182
[17]   Nutrient limitation is the main regulatory factor for carotenoid accumulation and for Psy and Pds steady state transcript levels in Dunaliella salina (Chlorophyta) exposed to high light and salt stress [J].
Coesel, Sacha Nicole ;
Baumgartner, Alexandra Cordeiro ;
Teles, Licia Marlene ;
Ramos, Ana Alexandra ;
Henriques, Nuno Miguel ;
Cancela, Leonor ;
Serafim Varela, Joao Carlos .
MARINE BIOTECHNOLOGY, 2008, 10 (05) :602-611
[18]   Carotenoids, antioxidants and ovarian cancer risk in pre- and postmenopausal women [J].
Cramer, DW ;
Kuper, H ;
Harlow, BL ;
Titus-Ernstoff, L .
INTERNATIONAL JOURNAL OF CANCER, 2001, 94 (01) :128-134
[19]  
Curtain C, 2000, PLANT BIOTECHNOLOGY
[20]  
Daliry S, 2017, GLOB J ENVIRON SCI M, V3, P217, DOI 10.22034/gjesm.2017.03.02.010