Factors affecting production of beta-carotene from Dunaliella salina microalgae

被引:87
作者
Pourkarimi, Sara [1 ]
Hallajisani, Ahmad [2 ]
Alizadehdakhel, Asghar [1 ]
Nouralishahi, Amideddin [2 ]
Golzary, Abooali [3 ]
机构
[1] Islamic Azad Univ, Rasht Branch, Dept Chem & Chem Engn, Rasht, Iran
[2] Univ Tehran, Sch Engn, Caspian Fac Engn, Biofuel Lab, Rezvanshahr Of Gilan, Iran
[3] Univ Tehran, Coll Engn, Sch Environm, POB 14155-6135, Tehran, Iran
关键词
Beta-carotene; Dunaliella salina; Extraction; Microalgae; Optimal condition; MOLECULAR-BIOLOGY; LOW-TEMPERATURE; ALGA; EXTRACTION; GROWTH; CHLOROPHYTA; EXPRESSION; STRAINS; GENE; PHOTOBIOREACTOR;
D O I
10.1016/j.bcab.2020.101771
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Dunaliella Salina is a carotene-producing microalgae well-known for its superb ability to accumulate valuable beta-carotene. The factors affecting the bio-beta-carotene production from Dunaliella salina microalgae have been investigated in this study. First, the different usages of Dunaliella salina, especially for the production of beta carotene, are described. Then, the factors affecting the process of obtaining beta-carotene from Dunaliella salina in the culture system, culture conditions, and downstream processes are investigated. Investigations show that application of airborne photo-bioreactor culture system improves the mechanism of production. It was found that among the culture conditions, the parameters such as ambient salinity, temperature, and intensity of illumination are the most effective ones. The optimal values for these parameters, the highest cellular density of Dunaliella salina and the highest beta-carotene production are determined. The extraction step is known as the most critical step in the downstream processes of beta-carotene production.
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页数:14
相关论文
共 97 条
[1]  
Abd El-Baky H.H., 2010, FOOD CHEM TOXICOL, DOI [10.1016/j.fct.2010.04.025, DOI 10.1016/J.FCT.2010.04.025]
[2]  
Abu-Rezq T.S., 2010, J ALGAL BIOMASS UTLN, V1, P12
[3]  
Al-Muhteseb S. I., 2015, Journal of Natural Sciences Research, V5, P53
[4]   Effect of high-rate algal ponds on viability of Cryptosporidium parvum oocysts [J].
Araki, S ;
Martín-Gomez, S ;
Bécares, E ;
De Luis-Calabuig, E ;
Rojo-Vazquez, F .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2001, 67 (07) :3322-3324
[5]   Carotenoids .2. Genetics and molecular biology of carotenoid pigment biosynthesis [J].
Armstrong, GA ;
Hearst, JE .
FASEB JOURNAL, 1996, 10 (02) :228-237
[6]   The role of carotenoids in consumer choice and the likely benefits from their inclusion into products for human consumption [J].
Baker, R ;
Günther, C .
TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2004, 15 (10) :484-488
[7]   Micro-algae as a source of protein [J].
Becker, E. W. .
BIOTECHNOLOGY ADVANCES, 2007, 25 (02) :207-210
[8]   Effect of low temperature on the stereoisomer composition of beta-carotene in the halotolerant alga Dunaliella bardawil (Chlorophyta) [J].
BenAmotz, A .
JOURNAL OF PHYCOLOGY, 1996, 32 (02) :272-275
[9]   Bioavailability of a natural isomer mixture compared with synthetic all-trans beta-carotene in human serum [J].
BenAmotz, A ;
Levy, Y .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1996, 63 (05) :729-734
[10]   Coupling and uncoupling of triglyceride and beta-carotene production by Dunaliella salina under nitrogen limitation and starvation [J].
Bonnefond, Hubert ;
Moelants, Nina ;
Talec, Amelie ;
Mayzaud, Patrick ;
Bernard, Olivier ;
Sciandra, Antoine .
BIOTECHNOLOGY FOR BIOFUELS, 2017, 10