Continuous-infusion high-dose leucovorin with 5-fluorouracil and cisplatin for relapsed metastatic breast cancer: A phase II study

被引：4

作者：

Booser, DJ ^{[1
]}

Walters, RS ^{[1
]}

Holmes, FA ^{[1
]}

Hortobagyi, GN ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA

来源：

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 2000年 / 23卷 / 01期

关键词：

leucovorin; 5-FU; cisplatin; breast cancer; relapse;

D O I：

10.1097/00000421-200002000-00011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twelve women with metastatic breast cancer were treated with continuous infusion high dose leucovorin, 5-fluorouracil and cisplatin. Toxicity was severe although the dose was lower than previously described for the treatment of other cancers, and there was little anti-tumor activity. Many other regimens are more effective and less toxic.

引用

页码：40 / 41

页数：2

共 50 条

[1] A PHASE-II STUDY OF CONTINUOUS-INFUSION 5-FLUOROURACIL AND LEUCOVORIN WITH WEEKLY CISPLATIN IN METASTATIC COLORECTAL-CARCINOMA
GREM, JL
MCATEE, N
BALIS, F
MURPHY, R
VENZON, D
KRAMER, B
GOLDSPIEL, B
BEGLEY, M
ALLEGRA, CJ
CANCER, 1993, 72 (03) : 663 - 668
[2] Outpatient weekly high-dose continuous-infusion 5-fluorouracil plus oral leucovorin in advanced colorectal cancer. A phase II trial
Aranda, E
Cervantes, A
Carrato, A
FernandezMartos, C
AntonTorres, A
Massuti, T
Barneto, I
GarciaConde, J
Baron, JM
DiazRubio, E
ANNALS OF ONCOLOGY, 1996, 7 (06) : 581 - 585
[3] A phase II study of continuous-infusion 5-fluorouracil with cisplatin and epirubicin in inoperable pancreatic cancer
Evans, TRJ
Lofts, FJ
Mansi, JL
Glees, JP
Dalgleish, AG
Knight, MJ
BRITISH JOURNAL OF CANCER, 1996, 73 (10) : 1260 - 1264
[4] RANDOMIZED PHASE II STUDY OF CISPLATIN AND HIGH-DOSE 5-FLUOROURACIL/LEUCOVORIN OR PACLITAXEL AND HIGH-DOSE 5-FLUOROURACIL/LEUCOVORIN IN LOCALLY ADVANCED OR METASTATIC GASTRIC CANCER AND ADENOCARCINOMAS OF THE GASTRO-OESOPHAGEAL JUNCTION
Luelmo, S.
Polee, M.
van Bochove, A.
Pruijt, H.
Ouwerkerk, J.
Sleeboom, H.
Tesselaar, M.
ANNALS OF ONCOLOGY, 2008, 19 : 173 - 174
[5] A PHASE-II TRIAL OF WEEKLY HIGH-DOSE CONTINUOUS-INFUSION 5-FLUOROURACIL PLUS ORAL LEUCOVORIN IN PATIENTS WITH ADVANCED COLORECTAL-CANCER
ARANDA, E
CERVANTES, A
DORTA, J
BLANCO, E
FERNANDEZMARTOS, C
CRUZHERNANDEZ, JJ
CARRATO, A
GONZALEZMANCHA, R
GARCIACONDE, J
DIAZRUBIO, E
CANCER, 1995, 76 (04) : 559 - 563
[6] Randomized, phase II study comparing cisplatin and high-dose 5-fluorouracil/leucovorin with paclitaxel and high-dose 5-fluorouracil/leucovorin in patients with advanced gastric cancer and adenocarcinomas of the gastroesophageal junction
Tesselaar, M. E.
Luelmo, S.
Polee, M.
van Bochove, A.
Ouwerkerk, J.
Pruijt, H.
Sleeboom, H.
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
[7] Vinorelbine, cisplatin and continuous infusion of 5-fluorouracil (ViFuP) in metastatic breast cancer patients:: A phase II study
Nolè, F
Munzone, E
Mandalà, M
Catania, C
Orlando, L
Zampino, MG
Minchella, I
Colleoni, M
Peruzzotti, G
Marrocco, E
Goldhirsch, A
ANNALS OF ONCOLOGY, 2001, 12 (01) : 95 - 100
[8] Phase II study of cisplatin, epirubicin, and continuous-infusion 5-fluorouracil for advanced biliary tract cancer
Morizane, C
Okada, S
Okusaka, T
Ueno, H
Saisho, T
ONCOLOGY, 2003, 64 (04) : 475 - 476
[9] Adjuvant Chemotherapy with Docetaxel, Cisplatin, and Continuous-Infusion 5-Fluorouracil for Gastric Cancer: A Phase II Study
Meng, Changting
Yin, Hongyan
Sun, Zhao
Zhou, Jianfeng
Chen, Shuchang
Bai, Chunmei
Zhao, Lin
TRANSLATIONAL ONCOLOGY, 2014, 7 (02): : 277 - 283
[10] A Phase II Study of Oxaliplatin, 5-Fluorouracil, Leucovorin, and High-Dose Capecitabine in Patients With Metastatic Colorectal Cancer
Lubner, Sam J.
LoConte, Noelle K.
Holen, Kyle D.
Schelman, William
Thomas, James P.
Jumonville, Alcee
Eickhoff, Jens C.
Seo, Songwon
Mulkerin, Daniel L.
CLINICAL COLORECTAL CANCER, 2010, 9 (03) : 157 - 161

← 1 2 3 4 5 →