Continuous-infusion high-dose leucovorin with 5-fluorouracil and cisplatin for relapsed metastatic breast cancer: A phase II study

被引：4

作者：

Booser, DJ ^{[1
]}

Walters, RS ^{[1
]}

Holmes, FA ^{[1
]}

Hortobagyi, GN ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA

来源：

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 2000年 / 23卷 / 01期

关键词：

leucovorin; 5-FU; cisplatin; breast cancer; relapse;

D O I：

10.1097/00000421-200002000-00011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twelve women with metastatic breast cancer were treated with continuous infusion high dose leucovorin, 5-fluorouracil and cisplatin. Toxicity was severe although the dose was lower than previously described for the treatment of other cancers, and there was little anti-tumor activity. Many other regimens are more effective and less toxic.

引用

页码：40 / 41

页数：2

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