Lewis acid catalyzed nitrile synthesis from aldehyde

被引：7

作者：

Bariya, Dipakkumar ^{[1
]}

Mishra, Satyendra ^{[1
]}

机构：

[1] Inst Adv Res, Dept Engn & Phys Sci, Gandhinagar 382426, Gujarat, India

来源：

TETRAHEDRON LETTERS | 2022年 / 94卷

关键词：

Calcium trifluoromethanesulfonate; Bu4NPF6; Aldehyde; Nitrile; Lewis catalyst; PRIMARY AMIDES; CONVERSION; DEHYDRATION; ALDOXIMES; ALCOHOLS; ANALOGS; AMMONIA; OXIMES; SYSTEM; MILD;

D O I：

10.1016/j.tetlet.2022.153711

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In DMA solvent, the one-pot conversion of aldehydes to their corresponding nitriles was studied in Lewis acid catalyst's system (Ca(OTf)(2)/Bu4NPF6) and hydroxylamine hydrochloride at 120 degrees C. The developed synthesis method was carried out under conventional heating conditions, and excellent product yields were obtained. (C) 2022 Elsevier Ltd. All rights reserved.

引用

页数：4

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