Sesquiterpene lactones from Algerian Artemisia herba-alba

被引:32
作者
Laid, Messai
Hegazy, Mohamed-Elamir F. [1 ]
Ahmed, Ahmed A.
Ali, Kalla
Belkacemi, Djaballah
Ohta, Shinji [2 ]
机构
[1] Natl Res Ctr, Chem Med Plant Dept, Cairo, Egypt
[2] Nagahama Inst Biosci & Technol, Shiga 5260829, Japan
关键词
Artemisia herba-alba; Sesquiterpene lactones;
D O I
10.1016/j.phytol.2008.04.002
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The phytochemical investigation of the methylene chloride/methanol extract of the aerial parts of Artemisia herba-alba afforded two new natural sesquiterpene lactones 1 beta,9 beta-diacetoxyeudesm-3-en-5 alpha,6 beta,11 beta H-12,6-olide (1) and 1 beta,9 beta-diacetoxyeudesm-4-en-6 beta,11 beta H-12,6-olide (2). The structures of the compounds were determined by comprehensive NMR studies, including DEPT, COSY, NOESY, HMQC, HMBC and HRMS. (c) 2008 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:85 / 88
页数:4
相关论文
共 12 条
[1]   EUDESMANOLIDES AND OTHER CONSTITUENTS FROM ARTEMISIA-HERBA-ALBA [J].
AHMED, AA ;
ABOUELELA, M ;
JAKUPOVIC, J ;
ELDIN, AAS ;
SABRI, N .
PHYTOCHEMISTRY, 1990, 29 (11) :3661-3663
[2]   Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis [J].
Bouwmeester, HJ ;
Wallaart, TE ;
Janssen, MHA ;
van Loo, B ;
Jansen, BJM ;
Posthumus, MA ;
Schmidt, CO ;
De Kraker, JW ;
König, WA ;
Franssen, MCR .
PHYTOCHEMISTRY, 1999, 52 (05) :843-854
[3]  
Davis SR, 1999, RECENT PROG HORM RES, V54, P185
[4]   Ferula harmonis 'zallouh' and enhancing erectile function in rats:: efficacy and toxicity study [J].
El-Thaher, TS ;
Matalka, KZ ;
Taha, HA ;
Badwan, AA .
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2001, 13 (04) :247-251
[5]   New trends in anti-malarial agents [J].
Frédérich, M ;
Dogné, JM ;
Angenot, L ;
De Mol, P .
CURRENT MEDICINAL CHEMISTRY, 2002, 9 (15) :1435-1456
[6]  
IGNATKOV VY, 1990, FARMAKOL TOKSIKOL, V53, P37
[7]  
Jiangsu College of New Medicine, 1977, COMPR DICT TRAD CHIN, P627
[8]   ANTIFERTILITY AND HORMONAL PROPERTIES OF CERTAIN CAROTANE SESQUITERPENES OF FERULA-JAESCHKEANA [J].
SINGH, MM ;
AGNIHOTRI, A ;
GARG, SN ;
AGARWAL, SK ;
GUPTA, DN ;
KESHRI, G ;
KAMBOJ, VP .
PLANTA MEDICA, 1988, (06) :492-494
[9]   EUDESMANOLIDES DERIVED FROM HERBOLIDE-B [J].
SOKOLOFF, S ;
SEGAL, R .
TETRAHEDRON, 1977, 33 (21) :2837-2841
[10]   Lignans and sesquiterpene lactones from Artemisia sieversiana and Inula racemosa [J].
Tan, RX ;
Tang, HQ ;
Hu, J ;
Shuai, B .
PHYTOCHEMISTRY, 1998, 49 (01) :157-161