Mercury exposure and its effects on fertility and pregnancy outcome

被引：66

作者：

Bjorklund, Geir ^{[1
]}

Chirumbolo, Salvatore ^{[2
,3
]}

Dadar, Maryam ^{[4
]}

Pivina, Lyudmila ^{[5
,6
]}

Lindh, Ulf ^{[7
]}

Butnariu, Monica ^{[8
,9
]}

Aaseth, Jan ^{[10
,11
]}

机构：

[1] Council Nutr & Environm Med CONEM, Toften 24, N-8610 Mo I Rana, Norway

[2] Univ Verona, Dept Neurosci Biomed & Movement Sci, Verona, Italy

[3] CONEM Sci Secretary, Verona, Italy

[4] AREEO, Razi Vaccine & Serum Res Inst, Karaj, Iran

[5] Semey Med Univ, Semey, Kazakhstan

[6] Semey Med Univ, CONEM Kazakhstan Environm Hlth & Safety Res Grp, Semey, Kazakhstan

[7] Uppsala Univ, Biol Educ Ctr, Uppsala, Sweden

[8] Banats Univ Agr Sci & Vet Med King Michael I Roma, Timisoara, Romania

[9] Banats Univ Agr Sci & Vet Med King Michael I Roma, CONEM Romania Biotechnol & Environm Sci Grp, Timisoara, Romania

[10] Innlandet Hosp Trust, Res Dept, Brumunddal, Norway

[11] Inland Norway Univ Appl Sci, Elverum, Norway

来源：

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY | 2019年 / 125卷 / 04期

关键词：

dental amalgam; dental personnel; fertility; foetus; mercury; HEALTH-RISK ASSESSMENT; UMBILICAL-CORD BLOOD; OCCUPATIONAL-EXPOSURE; HEAVY-METALS; BREAST-MILK; CHLORALKALI WORKERS; FISH CONSUMPTION; CADMIUM LEVELS; LOW-LEVEL; METHYLMERCURY EXPOSURE;

D O I：

10.1111/bcpt.13264

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Mercury (Hg), a highly toxic environmental pollutant, shows harmfulness which still represents a big concern for human health, including hazards to fertility and pregnancy outcome. Research has shown that Hg could induce impairments in the reproductive function, cellular deformation of the Leydig cells and the seminiferous tubules, and testicular degeneration as well as abnormal menstrual cycles. Some studies investigated spontaneous abortion and complicated fertility outcome due to occupational Hg exposure. Moreover, there is a relation between inhaled Hg vapour and reproductive outcome. This MiniReview evaluates the hypothesis that exposure to Hg may increase the risk of reduced fertility, spontaneous abortion and congenital deficits or abnormalities.

引用

页码：317 / 327

页数：11

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