[1] Univ Leeds, Inst Membrane & Syst Biol, Leeds LS2 9JT, W Yorkshire, England
[2] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England
[3] AstraZeneca, Alderley Pk, Cheshire, England
[4] Univ Leeds, Inst Mol & Cellular Biol, Leeds LS2 9JT, W Yorkshire, England