Seongomycin: A new sulfur-containing benzo[b]fluorene derived from genes clustered with those for kinamycin biosynthesis

被引:31
作者
Carney, JR
Hong, ST
Gould, SJ
机构
[1] OREGON STATE UNIV, DEPT CHEM, CORVALLIS, OR 97331 USA
[2] OREGON STATE UNIV, DEPT BIOCHEM & BIOPHYS, CORVALLIS, OR 97331 USA
关键词
D O I
10.1016/S0040-4039(97)00616-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Streptomyces lividans ZX7 transformed with a similar to 40 KB fragment of S, murayomaensis DNA produces the kinamycin biosynthetic intermediates kinobscurinone (I) and stealthin C (2a), as well as seongomycin (3), which had been previously observed in S, murayamaensis UV mutant MCl. (C) 1997 Elsevier Science Ltd.
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页码:3139 / 3142
页数:4
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