Cellular and molecular dissection of reperfusion injury - ROS within and without

被引:71
作者
Semenza, GL
机构
[1] Johns Hopkins Univ, Sch Med, Dept Pediat, Inst Med Genet, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Dept Med, Inst Med Genet, Baltimore, MD 21205 USA
关键词
apoptosis; ceramide; ischemia; tumor necrosis factor-alpha;
D O I
10.1161/01.RES.86.2.117
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:117 / 118
页数:2
相关论文
共 13 条
[1]   L-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes:: role of inhibition of ceramide generation [J].
Andrieu-Abadie, N ;
Jaffrézou, JP ;
Hatem, S ;
Laurent, G ;
Levade, T ;
Mercadier, JJ .
FASEB JOURNAL, 1999, 13 (12) :1501-1510
[2]   Stress signals for apoptosis: ceramide and c-Jun kinase [J].
Basu, S ;
Kolesnick, R .
ONCOGENE, 1998, 17 (25) :3277-3285
[3]  
Bielawska AE, 1997, AM J PATHOL, V151, P1257
[4]   Oxygen free radical signaling in ischemic preconditioning [J].
Das, DK ;
Engelman, RM ;
Maulik, N .
HEART IN STRESS, 1999, 874 :49-65
[5]   The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene [J].
Guo, Y ;
Jones, WK ;
Xuan, YT ;
Tang, XL ;
Bao, W ;
Wu, WJ ;
Han, H ;
Laubach, VE ;
Ping, PP ;
Yang, ZQ ;
Qiu, YM ;
Bolli, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (20) :11507-11512
[6]   Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes [J].
Hernandez, OM ;
Discher, DJ ;
Bishopric, NH ;
Webster, KA .
CIRCULATION RESEARCH, 2000, 86 (02) :198-204
[7]   T-lymphocyte-derived tumor necrosis factor exacerbates anoxia-reoxygenation-induced neutrophil-endothelial cell adhesion [J].
Kokura, S ;
Wolf, RE ;
Yoshikawa, T ;
Granger, DN ;
Aw, TY .
CIRCULATION RESEARCH, 2000, 86 (02) :205-213
[8]   p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes [J].
Long, XL ;
Boluyt, MO ;
Hipolito, MD ;
Lundberg, MS ;
Zheng, JS ;
ONeill, L ;
Cirielli, C ;
Lakatta, EG ;
Crow, MT .
JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (11) :2635-2643
[9]   Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin [J].
Mansat-De Mas, V ;
Bezombes, C ;
Quillet-Mary, A ;
Bettaïb, A ;
D'Orgeix, AD ;
Laurent, G ;
Jaffrézou, JP .
MOLECULAR PHARMACOLOGY, 1999, 56 (05) :867-874
[10]   Signal transduction of stress via ceramide [J].
Mathias, S ;
Peña, LA ;
Kolesnick, RN .
BIOCHEMICAL JOURNAL, 1998, 335 :465-480