Copper Hydride Catalyzed Reductive Aldol Addition/Lactonization Domino Reactions of α,β-Unsaturated Diesters

被引：11

作者：

Li, Zengchang ^{[1
]}

Zhang, Zhenlei ^{[1
]}

Yuan, Lu ^{[1
]}

Jiang, Lan ^{[1
]}

Li, Zhansheng ^{[2
]}

Li, Zhengning ^{[1
]}

机构：

[1] Dalian Univ, Coll Environm & Chem Engn, Dalian 116622, Peoples R China

[2] Dalian Univ Technol, Coll Chem Engn, Dalian 116023, Peoples R China

来源：

SYNLETT | 2014年 / 25卷 / 05期

关键词：

reductions; aldol reactions; lactones; domino reactions; copper; catalysis; CONJUGATE REDUCTION; STRYKERS REAGENT; KETONES; CYCLIZATIONS; DERIVATIVES; CARBOXYLATES; <(PH3P)CUH>6; COMPLEXES; (BDP)CUH; ACID;

D O I：

10.1055/s-0033-1340673

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first copper-catalyzed reductive aldol addition/lactonization domino reactions of alpha,beta-unsaturated dicarboxylate esters with ketones were achieved in high yields. The method, which involves easily available reagents, a flexible combination of reactants, and mild conditions, provides a simple route to functionalized lactones bearing an ester group.

引用

页码：724 / 728

页数：5

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