Improving Long-Term Outcomes After Liver Transplantation

被引:24
作者
Charlton, Michael R. [1 ]
机构
[1] Intermt Med Ctr, Dept Med, Murray, UT 84107 USA
关键词
Liver transplantation; Metabolic syndrome; Immunosuppression; Graft rejection; HEPATITIS-C VIRUS; ONSET DIABETES-MELLITUS; RISK-FACTORS; METABOLIC SYNDROME; RENAL-FUNCTION; FOLLOW-UP; MYCOPHENOLATE-MOFETIL; CRYPTOGENIC CIRRHOSIS; GRAFT-SURVIVAL; RECIPIENTS;
D O I
10.1016/j.cld.2014.05.011
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Long-term survival following liver transplantation is profoundly affected by conditions unrelated to graft function. Many causes of mortality are contributed to by the metabolic syndrome. The approach to metabolic syndrome in liver transplant recipients requires consideration of transplant-specific factors, particularly immunosuppression. Enhancing long-term outcomes for liver transplant recipients necessitates minimizing the amount of immunosuppression required to prevent rejection. Studies to determine the optimal approach to minimize the impact of metabolic syndrome and complications of immunosuppression in transplant recipients are needed.
引用
收藏
页码:717 / +
页数:15
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