Enantioselective synthesis of cyclopentenones via rhodium-catalyzed kinetic resolution and desymmetrization of 4-alkynals

被引：93
|
作者：
Tanaka, K [1 ]
Fu, GC [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 35期
关键词：
D O I：
10.1021/ja0266161
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed two new catalytic processes that provide efficient access to interesting chiral building blocks, cyclopentenones that bear tertiary and quaternary stereocenters, in high enantiomeric excess and very good yield. Structures such as these have potential utility in the synthesis of prostaglandins, pentenomycins, and related compounds. Copyright © 2002 American Chemical Society.
引用
收藏
页码：10296 / 10297
页数：2
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