Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives

被引：4

作者：

Sridevi, Ch. ^{[1
]}

Balaji, K. ^{[1
]}

Naidu, A. ^{[1
]}

Sudhakaran, R. ^{[1
]}

机构：

[1] Geethanjali Coll Pharm, Dept Pharmaceut Chem, Hyderabad 501301, Andhra Pradesh, India

来源：

E-JOURNAL OF CHEMISTRY | 2009年 / 6卷 / 03期

关键词：

2,3-Diphenyl quinoxaline; 2-Amino benzothiazole; Phenyl pyrazolo benzothiazolo quinoxaline; Antimicrobial activity;

D O I：

10.1155/2009/324358

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5). Chalcones refluxed with substituted acid hydrazides to afford different phenyl pyrazolo benzothiazolo quinoxaline derivatives (SVI1-SVI15). The structure of chalcones and phenyl pyrazolo benzothiazolo quinoxaline derivatives were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antimicrobial activities.

引用

页码：866 / 870

页数：5

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