Substrate-switched dual functionalization of alkenes: catalyst-free synthetic route for β-hydroxy and β-keto thioethers

被引：10
作者：
Badsara, Satpal Singh [1 ]
Singh, Pratibha [1 ]
Choudhary, Rakhee [1 ]
Bai, Rekha [1 ]
Sharma, Mahesh C. [1 ]
机构：
[1] Univ Rajasthan, Ctr Adv Study, Dept Chem, MFOS Lab, JLN Marg, Jaipur 302004, Rajasthan, India
来源：
NEW JOURNAL OF CHEMISTRY | 2019年 / 43卷 / 28期
关键词：
SULFENYLATED CARBONYL-COMPOUNDS; C-H FUNCTIONALIZATION; TRANSITION-METAL-FREE; ONE-POT SYNTHESIS; ACTIVATED ALKENES; EFFICIENT SYNTHESIS; BOND FORMATION; SULFUR; CLICK; DIFUNCTIONALIZATION;
D O I：
10.1039/c9nj02682g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this study, a substrate-controlled dual functionalization of alkenes under catalyst-free and solvent-free conditions is described. Alkenes possessing different electron-withdrawing groups, namely, ester and nitrile, reacted with a variety of thiols under air to provide beta-hydroxy thioethers and beta-keto thioethers, respectively, in good to excellent yields.
引用
收藏
页码：11045 / 11049
页数：5
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