Substrate-switched dual functionalization of alkenes: catalyst-free synthetic route for β-hydroxy and β-keto thioethers

被引：12

作者：

Badsara, Satpal Singh ^{[1
]}

Singh, Pratibha ^{[1
]}

Choudhary, Rakhee ^{[1
]}

Bai, Rekha ^{[1
]}

Sharma, Mahesh C. ^{[1
]}

机构：

[1] Univ Rajasthan, Ctr Adv Study, Dept Chem, MFOS Lab, JLN Marg, Jaipur 302004, Rajasthan, India

来源：

NEW JOURNAL OF CHEMISTRY | 2019年 / 43卷 / 28期

关键词：

SULFENYLATED CARBONYL-COMPOUNDS; C-H FUNCTIONALIZATION; TRANSITION-METAL-FREE; ONE-POT SYNTHESIS; ACTIVATED ALKENES; EFFICIENT SYNTHESIS; BOND FORMATION; SULFUR; CLICK; DIFUNCTIONALIZATION;

D O I：

10.1039/c9nj02682g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, a substrate-controlled dual functionalization of alkenes under catalyst-free and solvent-free conditions is described. Alkenes possessing different electron-withdrawing groups, namely, ester and nitrile, reacted with a variety of thiols under air to provide beta-hydroxy thioethers and beta-keto thioethers, respectively, in good to excellent yields.

引用

页码：11045 / 11049

页数：5

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