Use of estrogens for the prevention and treatment of Alzheimer's disease

被引：37
|
作者：
Monk, D
Brodaty, H [1 ]
机构：
[1] Prince Wales Hosp, Acad Dept Old Age Psychiat, Randwick, NSW 2031, Australia
[2] Univ New S Wales, Sch Psychiat, Sydney, NSW, Australia
来源：
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2000年 / 11卷 / 01期
关键词：
dementia; Alzheimer's disease; estrogens; cognition; treatment; prevention; central nervous system;
D O I：
10.1159/000017206
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
This review examines the biological rationale for the use of estrogen replacement therapy (ERT) and the evidence for the efficacy of ERT in enhancing cognition, preventing Alzheimer's disease (AD) and treating AD in postmenopausal women. While the biological basis for ERT as a cognition enhancer is strong and multiply mediated, the clinical evidence for its use is not as compelling and must be weighed against possible side effects. Until the results of definitive large trials are available, the use of ERT alone or in combination with other treatments is worthy of consideration. Copyright (C) 2000 S.Karger AG, Basel.
引用
收藏
页码：1 / 10
页数：10
相关论文
共 50 条
  • [31] Advances and challenges in the prevention and treatment of Alzheimer's disease
    Brinton, RD
    Yamazaki, RS
    PHARMACEUTICAL RESEARCH, 1998, 15 (03) : 386 - 398
  • [32] Estrogens and Alzheimer's disease: Is cholesterol a link?
    Etgen, Anne M.
    ENDOCRINOLOGY, 2008, 149 (09) : 4253 - 4255
  • [33] Prevention and treatment of Alzheimer disease
    Donoso S, Archibaldo
    Delgado D, Carolina
    REVISTA MEDICA DE CHILE, 2009, 137 (02) : 289 - 295
  • [34] Alzheimer's Disease Prevention and Use of Traditional Plant Medicines
    Wang, Xiaogang
    Dubois, Raphael
    Adams, James David, Jr.
    LETTERS IN DRUG DESIGN & DISCOVERY, 2015, 12 (02) : 140 - 151
  • [35] Leon Thal's vision for the treatment and prevention of Alzheimer's disease
    Weiner, Michael W.
    ALZHEIMERS & DEMENTIA, 2008, 4 (01) : S150 - S152
  • [36] Estrogen replacement therapy for the prevention and treatment of Alzheimer's disease
    Henderson, VW
    CNS DRUGS, 1997, 8 (05) : 343 - 351
  • [37] Estrogen Replacement Therapy for the Prevention and Treatment of Alzheimer’s Disease
    Victor W. Henderson
    CNS Drugs, 1997, 8 : 343 - 351
  • [38] New Frontiers in the Prevention, Diagnosis, and Treatment of Alzheimer's Disease
    Guzman-Martinez, Leonardo
    Calfio, Camila
    Farias, Gonzalo A.
    Vilches, Cristian
    Prieto, Raul
    Maccioni, Ricardo B.
    JOURNAL OF ALZHEIMERS DISEASE, 2021, 82 : S51 - S63
  • [39] Prevention of Alzheimer's disease
    Scheltens, P.
    JOURNAL OF NEUROLOGY, 2014, 261 : S8 - S8
  • [40] Prevention of Alzheimer's disease
    Szekely, C. A.
    Breitner, J. C. S.
    Zandi, P. P.
    INTERNATIONAL REVIEW OF PSYCHIATRY, 2007, 19 (06) : 693 - 706
12345