Unusual manifestation of posttransplant lymphoproliferative disorder in the esophagus

被引：8
作者：
Kranz, B.
Vester, U.
Becker, J.
Woltering, T.
Wingen, A. -M.
Paul, A.
Hoyer, P. F.
机构：
[1] Univ Duisburg Essen, Clin Pediat Nephrol, D-45122 Essen, Germany
[2] Univ Duisburg Essen, Dept Pathol, D-45122 Essen, Germany
[3] Univ Duisburg Essen, Dept Gen Surg & Transplantat, D-45122 Essen, Germany
来源：
TRANSPLANTATION PROCEEDINGS | 2006年 / 38卷 / 03期
关键词：
D O I：
10.1016/j.transproceed.2006.01.075
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Early manifestations of posttransplant lymphoproliferative disorders (PTLD) are mainly associated with a primary Epstein-Barr virus (EBV) infection. Rapid increases in peripheral blood EBV DNA load are supposed to reliably predict PTLD. We report a boy who 6 months after living-related kidney transplantation presented with an extranodal esophageal manifestation of PTLD. Despite a primary EBV infection with tonsillitis, the peripheral blood EBV DNA remained low, hiding the progression to PTLD.
引用
收藏
页码：693 / 696
页数：4
相关论文
共 7 条
  • [1] Risk factors for posttransplant lymphoproliferative disorder (PTLD) in pediatric kidney transplantation: A report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
    Dharnidharka, VR
    Sullivan, EK
    Stablein, DM
    Tejani, AH
    Harmon, WE
    [J]. TRANSPLANTATION, 2001, 71 (08) : 1065 - 1068
  • [2] Serial measurement of Epstein-Barr viral load in peripheral blood in pediatric liver transplant recipients during treatment for posttransplant lymphoproliferative disease
    Green, M
    Cacciarelli, TV
    Mazariegos, GV
    Sigurdsson, L
    Qu, L
    Rowe, DT
    Reyes, J
    [J]. TRANSPLANTATION, 1998, 66 (12) : 1641 - 1644
  • [3] EPSTEIN-BARR VIRUS-INFECTIONS AND DNA HYBRIDIZATION STUDIES IN POSTTRANSPLANTATION LYMPHOMA AND LYMPHOPROLIFERATIVE LESIONS - THE ROLE OF PRIMARY INFECTION
    HO, M
    MILLER, G
    ATCHISON, RW
    BREINIG, MK
    DUMMER, JS
    ANDIMAN, W
    STARZL, TE
    EASTMAN, R
    GRIFFITH, BP
    HARDESTY, RL
    BAHNSON, HT
    HAKALA, TR
    ROSENTHAL, JT
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1985, 152 (05) : 876 - 886
  • [4] Penn I, 1998, Pediatr Transplant, V2, P56
  • [5] SAVOIE A, 1994, BLOOD, V83, P2715
  • [6] The post-transplant lymphoproliferative disorder - a literature review
    Shroff, R
    Rees, L
    [J]. PEDIATRIC NEPHROLOGY, 2004, 19 (04) : 369 - 377
  • [7] Frequent monitoring of Epstein-Barr virus DNA load in unfractionated whole blood is essential for early detection of posttransplant lymphoproliferative disease in high-risk patients
    Stevens, SJC
    Verschuuren, EAM
    Pronk, I
    van der Bij, W
    Harmsen, MC
    The, TH
    Meijer, CJLM
    van den Brule, AJC
    Middeldorp, JM
    [J]. BLOOD, 2001, 97 (05) : 1165 - 1171
1