Peptide-directed self-assembly of hydrogels

被引:161
作者
Kopecek, Jindrich [1 ]
Yang, Jiyuan
机构
[1] Univ Utah, Dept Pharmaceut & Pharmaceut Chem, Salt Lake City, UT 84112 USA
关键词
Hydrogels; Self-assembly; Hybrid biomaterials; Peptides; Proteins; GENETICALLY-ENGINEERED PROTEIN; NONCANONICAL AMINO-ACIDS; CONTROLLED DRUG-DELIVERY; HYBRID BLOCK-COPOLYMERS; GLYCOL) STAR COPOLYMER; HELICAL COILED-COILS; CO-PEG NETWORKS; POLY(ETHYLENE GLYCOL); REVERSIBLE HYDROGELS; TRIBLOCK COPOLYMERS;
D O I
10.1016/j.actbio.2008.10.001
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This review focuses on the self-assembly of macromolecules mediated by the biorecognition of peptide/protein domains. Structures forming a-helices and P-sheets have been used to mediate self-assembly into hydrogels of peptides, reactive copolymers and peptide motifs, block copolymers, and graft copolymers. Structural factors governing the self-assembly of these molecules into precisely defined three-dimensional structures (hydrogels) are reviewed. The incorporation of peptide motifs into hybrid systems, composed of synthetic and natural macromolecules, enhances design opportunities for new biomaterials when compared to individual components. (c) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:805 / 816
页数:12
相关论文
共 118 条
[1]  
[Anonymous], [No title captured], Patent No. [3,361 858, 3361858]
[2]   In-lens cryo-high resolution scanning electron microscopy: Methodologies for molecular imaging of self-assembled organic hydrogels [J].
Apkarian, RP ;
Wright, ER ;
Seredyuk, VA ;
Eustis, S ;
Lyon, LA ;
Conticello, VP ;
Menger, FM .
MICROSCOPY AND MICROANALYSIS, 2003, 9 (04) :286-295
[3]   Elastin-based side-chain polymers synthesized by ATRP [J].
Ayres, L ;
Vos, MRJ ;
Adams, PJHM ;
Shklyarevskiy, IO ;
van Hest, JCM .
MACROMOLECULES, 2003, 36 (16) :5967-5973
[4]   Peptide and protein building blocks for synthetic biology: From programming biomolecules to self-organized biomolecular systems [J].
Bromley, Elizabeth H. C. ;
Channon, Kevin ;
Moutevelis, Efrosini ;
Woolfson, Derek N. .
ACS CHEMICAL BIOLOGY, 2008, 3 (01) :38-50
[5]   Structure of the β-amyloid(10-35) fibril [J].
Burkoth, TS ;
Benzinger, TLS ;
Urban, V ;
Morgan, DM ;
Gregory, DM ;
Thiyagarajan, P ;
Botto, RE ;
Meredith, SC ;
Lynn, DG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (33) :7883-7889
[6]   Self-assembly of Aβ(10-35)-PEG block copolymer fibrils [J].
Burkoth, TS ;
Benzinger, TLS ;
Urban, V ;
Lynn, DG ;
Meredith, SC ;
Thiyagarajan, P .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (32) :7429-7430
[7]   C-terminal PEG blocks the irreversible step in β-amyloid(10-35) fibrillogenesis [J].
Burkoth, TS ;
Benzinger, TLS ;
Jones, DNM ;
Hallenga, K ;
Meredith, SC ;
Lynn, DG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (30) :7655-7656
[8]   Responsive hybrid hydrogels with volume transitions modulated by a titin immunoglobulin module [J].
Chen, L ;
Kopecek, J ;
Stewart, RJ .
BIOCONJUGATE CHEMISTRY, 2000, 11 (05) :734-740
[9]   Self-assembling polymer-peptide conjugates: Nanostructural tailoring [J].
Collier, JH ;
Messersmith, PB .
ADVANCED MATERIALS, 2004, 16 (11) :907-910
[10]   Thermally and photochemically triggered self-assembly of peptide hydrogels [J].
Collier, JH ;
Hu, BH ;
Ruberti, JW ;
Zhang, J ;
Shum, P ;
Thompson, DH ;
Messersmith, PB .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (38) :9463-9464