Synthesis of 4-oxo-2-thioxohexahydropyriniidines under ultrasound irradiation

被引：0

作者：

Li, JT ^{[1
]}

Han, JF ^{[1
]}

Lin, ZP ^{[1
]}

Li, TS ^{[1
]}

机构：

[1] Hebei Univ, Coll Chem & Environm Sci, Key Lab Analyt Sci & Technol, Baoding 071002, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 24卷 / 06期

关键词：

4-oxo-2-thioxohexahydropyrimidine; synthesis; ultrasound irradiation;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Under ultrasound irradiation, the cyclocondensation of ethyl alpha-cyanocinnamates with thiourea activated by potassium carbonate at room temperature in ethanol resulted in 4-oxo-2-thioxohexahydropyrimidines in good yields. The advantages of the procedure are short reaction period, high yield and simple work-up.

引用

页码：675 / 679

页数：5

共 20 条

[1] Bian YJ, 2002, CHINESE J ORG CHEM, V22, P227
[2] CHABRE M, 1966, B SOC CHIM FR, P108
[3] CRYSTAL AND MOLECULAR STRUCTURE OF DIHYDROTHYMINE
FURBERG, S
JENSEN, LH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (02) : 470 - &
[4] BETA-UREIDO ACIDS AND DIHYDROURACILS .7. APPLICATIONS OF PROTON RESONANCE SPECTROSCOPY .32. NMR SPECTRA AND CONFORMATION OF DIHYDROURACILS AND RELATED COMPOUNDS
KATRITZKY, AR
NESBIT, MR
KURTEV, BJ
LYAPOVA, M
POJARLIEFF, IG
[J]. TETRAHEDRON, 1969, 25 (17) : 3807 - +
[5] Li JT, 2003, CHINESE J ORG CHEM, V23, P1428
[6] Li JT, 2003, CHINESE J ORG CHEM, V23, P479
[7] An efficient synthesis of 3,4-dihydropyrimidin-2-ones catalyzed by NH2SO3H under ultrasound irradiation
Li, JT
Han, JF
Yang, JH
Li, TS
[J]. ULTRASONICS SONOCHEMISTRY, 2003, 10 (03) : 119 - 122
[8] SYNTHETIC AND CONFORMATIONAL STUDIES ON 5,6-SUBSTITUTED DIHYDRO-2-THIOURACILS
LORENTE, A
AURRECOECHEA, LM
[J]. HETEROCYCLES, 1994, 38 (05) : 1077 - 1087
[9] LORENTE A, 1985, SYNTHESIS-STUTTGART, P89
[10] Lu J, 2001, CHINESE J ORG CHEM, V21, P640

← 1 2 →