Arsenite and methylarsonite impair glucose-stimulated insulin secretion through inhibition of mitochondrial respiration and calcium influx

被引:1
|
作者
Dover, E. N. [1 ]
Huang, M. C. [1 ]
Douillet, C. [2 ]
Styblo, M. [1 ,2 ]
机构
[1] Curriculum Toxicol, Chapel Hill, NC USA
[2] Univ North Carolina Chapel Hill, Dept Nutr, Chapel Hill, NC USA
关键词
D O I
10.1016/j.toxlet.2016.07.376
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
PO16.4
引用
收藏
页码:S158 / S158
页数:1
相关论文
共 50 条
  • [1] Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells
    E. N. Dover
    R. Beck
    M. C. Huang
    C. Douillet
    Z. Wang
    E. L. Klett
    Miroslav Stýblo
    Archives of Toxicology, 2018, 92 : 693 - 704
  • [2] Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells
    Dover, E. N.
    Beck, R.
    Huang, M. C.
    Douillet, C.
    Wang, Z.
    Klett, E. L.
    Styblo, Miroslav
    ARCHIVES OF TOXICOLOGY, 2018, 92 (02) : 693 - 704
  • [3] Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets
    Huang, Madelyn
    Douillet, Christelle
    Styblo, Miroslav
    ARCHIVES OF TOXICOLOGY, 2019, 93 (09) : 2525 - 2533
  • [4] Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets
    Madelyn Huang
    Christelle Douillet
    Miroslav Stýblo
    Archives of Toxicology, 2019, 93 : 2525 - 2533
  • [5] Importance of beta cell mitochondrial calcium in glucose-stimulated insulin secretion
    Wollheim, Claes B.
    ENDOCRINE JOURNAL, 2010, 57 : S215 - S216
  • [6] Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets
    Jing, Muhan
    Wang, Shanshan
    Li, Ding
    Wang, Zeyu
    Li, Ziwen
    Lu, Yichen
    Sun, Tong
    Qiu, Chen
    Chen, Fang
    Yu, Haijuan
    Zhang, Wei
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [7] Olanzapine Treatment Does Not Impair Glucose-Stimulated Insulin Secretion
    Kim, Sun H.
    Nikolics, Lilla
    Abbasi, Fahim
    Lamendola, Cindy
    Reaven, Gerald
    Lindley, Steven
    DIABETES, 2009, 58 : A611 - A611
  • [8] Low doses of hydrogen peroxide impair glucose-stimulated insulin secretion via inhibition of glucose metabolism and intracellular calcium oscillations
    Rebelato, Eduardo
    Abdulkader, Fernando
    Curi, Rui
    Carpinelli, Angelo R.
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2010, 59 (03): : 409 - 413
  • [9] Mitochondrial GTP regulates glucose-stimulated insulin secretion
    Kibbey, Richard G.
    Pongratz, Rebecca L.
    Romanelli, Anthony J.
    Wollheim, Claes B.
    Cline, Gary W.
    Shulman, Gerald I.
    CELL METABOLISM, 2007, 5 (04) : 253 - 264
  • [10] Low extracellular magnesium does not impair glucose-stimulated insulin secretion
    Gommers, Lisanne M. M.
    Hill, Thomas G.
    Ashcroft, Frances M.
    de Baaij, Jeroen H. F.
    PLOS ONE, 2019, 14 (06):