Preparation and application of chitosan biomaterials in dentistry

被引:54
作者
Zhang, Chenxi [1 ]
Hui, Didi [2 ]
Du, Colin [2 ]
Sun, Huan [3 ,4 ]
Peng, Wei [5 ,6 ]
Pu, Xiaobing [5 ,6 ]
Li, Zhengyong [7 ]
Sun, Jianxun [1 ]
Zhou, Changchun [3 ,4 ]
机构
[1] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu 610041, Peoples R China
[2] Innovatus Oral Cosmet & Surg Inst, Norman, OK 73069 USA
[3] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China
[4] Sichuan Univ, Coll Biomed Engn, Chengdu 610064, Peoples R China
[5] Sichuan Univ Chengdu, West China Sch Publ Hlth, Chengdu 610041, Sichuan, Peoples R China
[6] Sichuan Univ Chengdu, West China Hosp 4, Chengdu 610041, Sichuan, Peoples R China
[7] Sichuan Univ, West China Hosp, West China Sch Med, Dept Burn & Plast Surg, Chengdu 610041, Peoples R China
基金
中国国家自然科学基金;
关键词
Biomaterials; Chitosan; Oral disease; SELF-ASSEMBLED NANOPARTICLES; BIOFILM FORMATION; DELIVERY; ANTIBACTERIAL; TISSUE; HEMOSTASIS; EFFICIENT; RELEASE; BONE; PARAMETERS;
D O I
10.1016/j.ijbiomac.2020.11.073
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chitosan is a biodegradable and biocompatible natural polysaccharide that has awide range of applications in the field of dentistry due to its functional versatility and ease of access. Recent studies find that chitosan and its derivatives can beembedded inmaterials for dental adhesives, barriermembranes, bone replacement, tissue regeneration, and antimicrobial agent to better manage oral diseases. In this paper, we provide a comprehensive overview on the preparation, applications, and major breakthroughs of chitosan biomaterials. Furthermore, incorporation of chitosan additives for the modification and improvement of dental materials has been discussed in depth to promote more advanced chitosan-related research in the future. (C) 2020 Published by Elsevier B.V.
引用
收藏
页码:1198 / 1210
页数:13
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