Within-farm spread of classical swine fever virus -: A blueprint for a stochastic simulation model

被引:0
作者
Stärk, KDC [1 ]
Pfeiffer, DU [1 ]
Morris, RS [1 ]
机构
[1] Massey Univ, Inst Vet Anim & Biomed Sci, EpiCtr, Palmerston North, New Zealand
关键词
hog cholera; transmission; computer simulation;
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A stochastic simulation model to investigate the transmission of classical swine fever (CSF) virus within an infected farm is described. The model is structured according to the processes that occur within and between management groups (pig units or houses). It uses the individual pig as the unit of interest and estimates the number of animals in the states 'susceptible', 'infected', 'infectious', and 'removed' for each day of the disease incident. Probabilities are assigned to the transitions between states. The probability of a pig becoming infected is made dependent on the probability of contact between a susceptible and an infectious pig as well. as the probability of transmission. The more pigs become infected in one unit, the more likely is subsequent spread to another management group on the farm. Ultimately, the probability that a shipment of pigs from the farm will include at least one infected pig can be estimated in order to identify high-risk movements during a CSF epidemic. The model results were compared,vith experimental data on CSF transmission within one pig unit (management group). It could be shown that the model was capable of reproducing the experimentally observed infection and mortality rates. To improve the input parameters and for further model validation, more experimental data and field data from CSF outbreaks are needed.
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页码:36 / 43
页数:8
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共 41 条
[1]   POPULATION BIOLOGY OF INFECTIOUS-DISEASES .1. [J].
ANDERSON, RM ;
MAY, RM .
NATURE, 1979, 280 (5721) :361-367
[2]  
Bouma A, 1996, AM J VET RES, V57, P43
[3]   TRANSMISSION OF PSEUDORABIES VIRUS WITHIN PIG-POPULATIONS IS INDEPENDENT OF THE SIZE OF THE POPULATION [J].
BOUMA, A ;
DEJONG, MCM ;
KIMMAN, TG .
PREVENTIVE VETERINARY MEDICINE, 1995, 23 (3-4) :163-172
[4]  
DAHLE J, 1995, WIEN TIERARZTL MONAT, V82, P232
[5]   A REVIEW ON CLASSICAL SWINE FEVER INFECTIONS IN PIGS - EPIZOOTIOLOGY, CLINICAL-DISEASE AND PATHOLOGY [J].
DAHLE, J ;
LIESS, B .
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 1992, 15 (03) :203-211
[6]   THE COMPUTATION OF R(0) FOR DISCRETE-TIME EPIDEMIC MODELS WITH DYNAMIC HETEROGENEITY [J].
DEJONG, MCM ;
DIEKMANN, O ;
HEESTERBEEK, JAP .
MATHEMATICAL BIOSCIENCES, 1994, 119 (01) :97-114
[7]  
DEPNER K, 1994, WIEN TIERARZTL MONAT, V81, P370
[8]   Influence of breed-related factors on the course of classical swine fever virus infection [J].
Depner, KR ;
Hinrichs, U ;
Bickhardt, K ;
GreiserWilke, I ;
Pohlenz, J ;
Moennig, V ;
Liess, B .
VETERINARY RECORD, 1997, 140 (19) :506-507
[9]  
DEPNER KR, 1995, TIERAERZTL UMSCHAU, V50, P571
[10]  
GRENFELL BT, 1990, AM J VET RES, V51, P156