Complete control of the chemoselectivity in catalytic carbene transfer reactions from ethyl diazoacetate:: An N-heterocyclic carbene-Cu system that suppresses diazo coupling

被引：114

作者：

Fructos, MR

Belderrain, TR

Nicasio, MC

Nolan, SP

Kaur, H

Díaz-Requejo, MM

Pérez, PJ

机构：

[1] Univ Huelva, Dept Quim & Ciencia Mat, Huelva 21007, Spain

[2] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 35期

关键词：

D O I：

10.1021/ja047284y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The complex IPrCuCl (1) catalyzes the transfer of the :CHCO2Et group from ethyl diazoacetate (EDA) to unsaturated and saturated substrates (olefins, amine, alcohols) with very high yields. In the absence of substrate, the complex 1 does not react with EDA to give the diazo coupling products (fumarate and maleate), a rare example in the field of metal-catalyzed diazocompounds decomposition. Copyright © 2003 American Chemical Society.

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页码：10846 / 10847

页数：2

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