Glypetelotine, a sulphur-containing indole alkaloid from Glycosmis petelotii

被引：16

作者：

Cuong, NM

Taylor, WC

Sung, TV

机构：

[1] Vietnam Natl Ctr Nat Sci & Technol, Inst Chem, Hanoi, Vietnam

[2] Univ Sydney, Sch Chem, Dept Organ Chem, Sydney, NSW 2006, Australia

来源：

PHYTOCHEMISTRY | 1999年 / 52卷 / 08期

关键词：

Glycosmis petelotii; Rutaceae; glypetelotine; indole; sulphur-containing alkaloid; thiocarbamate;

D O I：

10.1016/S0031-9422(99)00402-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A sulphur-containing indole alkaloid, glypetelotine, has been isolated fi om the leaves of the endemic Vietnamese plant Glycosmis petelotii Guill. (Rutaceae). The structure of glypetelotine was determined to be S-methyl N,N-2-[(1H)-indol-3-ethyl]methyl thiocarbamate from the spectroscopic evidence including UV, IR, MS,H-1- and C-13-NMR, NOESY, HETCOR and DQF-H-1-H-1 COSY. Conformational isomerism of the compound, resulting from the tertiary amide-like unit, was studied by dynamic H-1-NMR spectroscopy carried out in different solvents and at different temperatures. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1711 / 1714

页数：4

共 11 条

[1] GLYCOZOLIDOL, AN ANTIBACTERIAL CARBAZOLE ALKALOID FROM GLYCOSMIS-PENTAPHYLLA [J].