Vaccines against tropical parasitic diseases: a persisting answer to a persisting problem

被引：59

作者：

Sacks, David L. ^{[1
]}

机构：

[1] NIAID, Parasit Dis Lab, NIH, Bethesda, MD 20892 USA

来源：

NATURE IMMUNOLOGY | 2014年 / 15卷 / 05期

关键词：

LONG-TERM IMMUNITY; T-CELL IMMUNITY; PROTECTIVE IMMUNITY; IRRADIATED SPOROZOITES; LEISHMANIA-MAJOR; MALARIA; MEMORY; IMMUNIZATION; CD8(+); MAINTENANCE;

D O I：

10.1038/ni.2853

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Live whole-organism vaccines against Plasmodium falciparum malaria and cutaneous leishmaniasis remain the most uniformly effective vaccines against human parasitic diseases. These vaccines are discussed in terms of the requirement for persisting antigen to generate and maintain a protective response. © 2014 Nature America, Inc.

引用

页码：403 / 405

页数：3

共 25 条

[1] New vaccines for neglected parasitic diseases and dengue [J].

Beaumier, Coreen M. ;

Gillespie, Portia M. ;

Hotez, Peter J. ;

Bottazzi, Maria Elena .

TRANSLATIONAL RESEARCH, 2013, 162 (03) :144-155

[2] CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity [J].

Belkaid, Y ;

Piccirillo, CA ;

Mendez, S ;

Shevach, EM ;

Sacks, DL .

NATURE, 2002, 420 (6915) :502-507

[3] IMMUNIZATION OF MAN AGAINST SPOROZITE-INDUCED FALCIPARUM MALARIA [J].

CLYDE, DF ;

MOST, H ;

MCCARTHY, VC ;

VANDERBERG, JP .

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1973, 266 (03) :169-177

[4] Prolonged Antigen Presentation Is Required for Optimal CD8+T Cell Responses against Malaria Liver Stage Parasites [J].

Cockburn, Ian A. ;

Chen, Yun-Chi ;

Overstreet, Michael G. ;

Lees, Jason R. ;

van Rooijen, Nico ;

Farber, Donna L. ;

Zavala, Fidel .

PLOS PATHOGENS, 2010, 6 (05) :1-13

[5] Short-Lived Effector CD8 T Cells Induced by Genetically Attenuated Malaria Parasite Vaccination Express CD11c [J].

Cooney, Laura A. ;

Gupta, Megha ;

Thomas, Sunil ;

Mikolajczak, Sebastian ;

Choi, Kimberly Y. ;

Gibson, Claire ;

Jang, Ihn K. ;

Danziger, Sam ;

Aitchison, John ;

Gardner, Malcolm J. ;

Kappe, Stefan H. I. ;

Wang, Ruobing .

INFECTION AND IMMUNITY, 2013, 81 (11) :4171-4181

[6] Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation [J].

Ewer, Katie J. ;

O'Hara, Geraldine A. ;

Duncan, Christopher J. A. ;

Collins, Katharine A. ;

Sheehy, Susanne H. ;

Reyes-Sandoval, Arturo ;

Goodman, Anna L. ;

Edwards, Nick J. ;

Elias, Sean C. ;

Halstead, Fenella D. ;

Longley, Rhea J. ;

Rowland, Rosalind ;

Poulton, Ian D. ;

Draper, Simon J. ;

Blagborough, Andrew M. ;

Berrie, Eleanor ;

Moyle, Sarah ;

Williams, Nicola ;

Siani, Loredana ;

Folgori, Antonella ;

Colloca, Stefano ;

Sinden, Robert E. ;

Lawrie, Alison M. ;

Cortese, Riccardo ;

Gilbert, Sarah C. ;

Nicosia, Alfredo ;

Hill, Adrian V. S. .

NATURE COMMUNICATIONS, 2013, 4

[7] Peripheral tissue surveillance and residency by memory T cells [J].

Gebhardt, Thomas ;

Mueller, Scott N. ;

Heath, William R. ;

Carbone, Francis R. .

TRENDS IN IMMUNOLOGY, 2013, 34 (01) :27-32

[8] Vaccines against malaria [J].

Hill, Adrian V. S. .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2011, 366 (1579) :2806-2814

[9] Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory [J].

Homann, D ;

Teyton, L ;

Oldstone, MBA .

NATURE MEDICINE, 2001, 7 (08) :913-919

[10] The antipoverty vaccines [J].

Hotez, Peter J. ;

Ferris, Meghan T. .

VACCINE, 2006, 24 (31-32) :5787-5799

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