Identification of long non-coding RNAs in insects genomes

被引:34
|
作者
Legeai, Fabrice [1 ,2 ]
Derrien, Thomas [3 ]
机构
[1] INRA, UMR1349, Inst Genet Environm & Plant Protect, Domaine Motte, BP35327, F-35653 Le Rheu, France
[2] IRISA INRIA GenScale, F-35000 Rennes, France
[3] Univ Rennes 1, CNRS, UMR 6290, Inst Genet & Dev Rennes, F-35000 Rennes, France
关键词
DIFFERENTIAL EXPRESSION; ULTRABITHORAX DOMAIN; DROSOPHILA; TRANSCRIPTS; SEQ; EVOLUTION; REVEALS; ALIGNMENT; GENES; RECONSTRUCTION;
D O I
10.1016/j.cois.2015.01.003
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The development of high throughput sequencing technologies (HTS) has allowed researchers to better assess the complexity and diversity of the transcriptome. Among the many classes of non-coding RNAs (ncRNAs) identified the last decade, long non-coding RNAs (lncRNAs) represent a diverse and numerous repertoire of important ncRNAs, reinforcing the view that they are of central importance to the cell machinery in all branches of life. Although lncRNAs have been involved in essential biological processes such as imprinting, gene regulation or dosage compensation especially in mammals, the repertoire of lncRNAs is poorly characterized for many non-model organisms. In this review, we first focus on what is known about experimentally validated lncRNAs in insects and then review bioinformatic methods to annotate lncRNAs in the genomes of hexapods.
引用
收藏
页码:37 / 44
页数:8
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