Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity

被引：225
作者：
Sivaraj, Rajeshwari [1 ,2 ]
Rahman, Pattanathu K. S. M. [1 ]
Rajiv, P. [2 ]
Narendhran, S. [2 ]
Venckatesh, R. [3 ]
机构：
[1] Univ Teesside, Sch Sci & Engn, Middlesbrough TS1 3BA, Tees Valley, England
[2] Karpagam Univ, Sch Life Sci, Dept Biotechnol, Coimbatore 641021, Tamil Nadu, India
[3] Govt Arts Coll, Fac Chem, Udumalpet 642126, Tamil Nadu, India
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2014年 / 129卷
关键词：
Acalypha indica; Antimicrobial; Biological method; Copper oxide nanoparticles; Cytotoxicity; ANTIBACTERIAL; NANOCLUSTERS; AG;
D O I：
10.1016/j.saa.2014.03.027
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MIT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity. (C) 2014 Elsevier B.V. All rights reserved.
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收藏
页码：255 / 258
页数：4
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