Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices

被引：78

作者：

Liese, J. G. ^{[1
]}

Silfverdal, S. A. ^{[2
]}

Giaquinto, C. ^{[3
]}

Carmona, A. ^{[4
]}

Larcombe, J. H. ^{[5
,6
]}

Garcia-Sicilia, J. ^{[7
]}

Fuat, A. ^{[8
,9
]}

Garces-Sanchez, M. ^{[10
]}

Arroba Basanta, M. L. ^{[11
]}

Munoz Hiraldo, E. ^{[12
]}

Cantarutti, L. ^{[13
]}

Kroeniger, W. ^{[14
]}

Vollmar, J. ^{[14
]}

Holl, K. ^{[15
]}

Pircon, J. Y. ^{[15
]}

Rosenlund, M. R. ^{[15
,16
]}

机构：

[1] Univ Childrens Hosp, Dept Paediat Infect Dis & Immunol, D-97080 Wurzburg, Germany

[2] Umea Univ, Dept Clin Sci, Umea, Sweden

[3] Univ Padua, Dept Paediat, I-35100 Padua, Italy

[4] Inst Hispalense Pediat, Seville, Spain

[5] Harbinson House Surg, Sedgefield, Durham, England

[6] Univ Durham, Ctr Integrated Hlth Care Res, Durham DH1 3HP, England

[7] Hosp Materno Infantil La Paz, Madrid, Spain

[8] Univ Durham, Durham, England

[9] Carmel Med Practice, Durham, England

[10] Nazaret Hlth Ctr, Dept Paediat, Valencia, Spain

[11] CS Pozuelo Univ Autonoma Madrid, Madrid, Spain

[12] Hlth Ctr Dr Castroviejo, Dept Pediat, Madrid, Spain

[13] Family Paediatrician Pedianet Project, Padua, Italy

[14] GlaxoSmithKline Vaccines, Munich, Germany

[15] GlaxoSmithKline Vaccines, Wavre, Belgium

[16] Karolinska Inst, Dept Med, Clin Epidemiol Unit, Ctr Pharmacoepidemiol, S-10401 Stockholm, Sweden

来源：

EPIDEMIOLOGY AND INFECTION | 2014年 / 142卷 / 08期

关键词：

Acute otitis media; children; Europe; PROSPECTIVE OBSERVATIONAL COHORT; PNEUMOCOCCAL CONJUGATE VACCINE; HAEMOPHILUS-INFLUENZAE; PRIMARY-CARE; BURDEN; EPIDEMIOLOGY; DISEASE; IMPACT; LIFE;

D O I：

10.1017/S0950268813002744

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We conducted an epidemiological, observational cohort study to determine the incidence and complications of acute otitis media (AOM) in children aged <6 years. Data on physician-diagnosed AOM were collected from retrospective review of medical charts for the year preceding enrolment and then prospectively in the year following enrolment. The study included 5776 children in Germany, Italy, Spain, Sweden, and the UK. AOM incidence was 256/1000 person-years [95% confidence interval (CI) 243-270] in the prospective study period. Incidence was lowest in Italy (195, 95% CI 171-222) and highest in Spain (328, 95% CI 296-363). Complications were documented in < 1% of episodes. Spontaneous tympanic membrane perforation was documented in 7% of episodes. Both retrospective and prospective study results were similar and show the high incidence during childhood in these five European countries. Differences by country may reflect true differences and differences in social structure and diagnostic procedures.

引用

页码：1778 / 1788

页数：11

共 30 条

[1]

Caceres Udina Ma J, 2004, An Pediatr (Barc), V60, P133

[2] Changes in frequency and pathogens causing acute otitis media in 1995-2003 [J].

Casey, JR ;

Pichichero, ME .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2004, 23 (09) :824-828

[3]

COHEN R, 1996, MED ENFANCE, V6, P27

[4] Long-term prognosis of acute otitis media in infancy: determinants of recurrent acute otitis media and persistent middle ear effusion [J].

Damoiseaux, RAMJ ;

Rovers, MM ;

Van Balen, FAM ;

Hoes, AW ;

de Melker, RA .

FAMILY PRACTICE, 2006, 23 (01) :40-45

[5] Efficacy of a pneumococcal conjugate vaccine against acute otitis media [J].

Eskola, J ;

Kilpi, T ;

Palmu, A ;

Jokinen, J ;

Haapakoski, J ;

Herva, E ;

Takala, A ;

Käyhty, H ;

Karma, P ;

Kohberger, R ;

Siber, G ;

Mäkela, PH ;

Lockhart, S ;

Ecrola, M .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (06) :403-409

[6] Impact of the pneumococcal conjugate vaccine on otitis media [J].

Fireman, B ;

Black, SB ;

Shinefield, HR ;

Lee, J ;

Lewis, E ;

Ray, P .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2003, 22 (01) :10-16

[7]

FRANCOIS M, 2008, REUN INT CHIM ANT PA

[8]

Garces-Sanchez M, 2004, An Pediatr (Barc), V60, P125

[9]

Garces-Sanchez M D, 2005, An Pediatr (Barc), V63, P125

[10] Challenges in reducing the burden of otitis media disease: An ENT perspective on improving management and prospects for prevention [J].

Grevers, Gerhard .

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2010, 74 (06) :572-577

← 1 2 3 →

Incidence and clinical presentation of acute otitis media in children aged &lt;6 years in European medical practices

Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices