Background: This integrative review appraises the literature that explores the experiences of the adolescentdiagnosed with cancer. Background: The cancer experience has an impact on the way the adolescent lives their life, their futurehopes dreams and fears, their health and wellbeing. Healthcare professionals require an understandingof what the adolescent experiences after a diagnosis of cancer and during the treatment experience tobe able to provide optimal age appropriate care. Methods: The review was conducted following Whittemore and Knafl's (2005) framework. A comprehensive search using the following four databases, CINAHL, MEDLINE, PyschINFO, Embase was undertakenfor the period of 2005-2016. Google scholar, healthcare policies and guidelines reference lists were alsosearched. Screening and appraisal of 911 articles resulted in 22 articles being included in this review. Findings: Three themes were identified: 'Losing what I know -this is what makes me different', 'Communication and information sharing -the need to know', and 'The importance of friends, peers andrelationships'. Conclusion: This review reports that healthcare providers should be aware of the changing selfperceptions the adolescent experiences throughout the cancer journey. Accessing this information willenable healthcare providers to determine more appropriate care when these adolescents are feeling mostvulnerable. The review identified there is limited information about the experience of the younger adolescent (11-15 years) with cancer. Future research may benefit from focusing on the stage of developmentof the adolescent with cancer. (c) 2019 Australian College of Nursing Ltd. Published by Elsevier Ltd.