Fabrication of hydrogels with nanoparticles as surface-enhanced Raman scattered (SERS) substrates and their application in Raman imaging

被引:9
作者
Wu, Chaochao [1 ]
Li, Fang [1 ]
Lv, Feng [2 ]
Yao, Pei [1 ,3 ]
Bi, Minghai [3 ]
Xue, Tao [1 ,3 ]
机构
[1] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China
[2] Chinese Acad Med Sci, Inst Biomed Engn, Tianjin 300192, Peoples R China
[3] Tianjin Univ, Ctr Anal, Tianjin 300072, Peoples R China
基金
中国国家自然科学基金;
关键词
hydrogel; SERS; crystal violet; Raman imaging; Ag NPs; SINGLE-MOLECULE; AG; AU; ASSEMBLIES; FILMS;
D O I
10.1088/2053-1591/abd5d0
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A polyvinyl alcohol-silver nanoparticle (PVA-Ag NP) hydrogel was fabricated using a simple and facile method; it was used as a substrate for surface-enhanced Raman scattering (SERS). The Ag+ ions dispersed uniformly in the PVA network were reduced by NaBH4; this process was termed dipping method. Compared with conventional SERS substrates (e.g., colloidal suspensions), the prepared PVA-Ag NP hydrogel has prominent Raman enhancement effects for crystal violet (CV), and the detection limit was 10(-12) M. It could also help detect rhodamine B, methylene blue, and 4-mercaptobenzoic acid. In addition to SERS, the reliable 3D porous structure was utilized in the Raman imaging of CV at 1621 cm(-1) in a nude mouse.
引用
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页数:8
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