Preparation of black soybean (Glycine max L) extract with enhanced levels of phenolic compound and estrogenic activity using high hydrostatic pressure and pre-germination

被引:10
作者
Kim, Min Young [1 ]
Jang, Gwi Yeong [1 ]
Lee, Sang Hoon [2 ]
Kim, Kyung Mi [2 ]
Lee, Junsoo [1 ]
Jeong, Heon Sang [1 ]
机构
[1] Chungbuk Natl Univ, Dept Food Sci & Biotechnol, 1 Chungdaero, Cheongju 361763, South Korea
[2] Natl Acad Agr Sci, Rural Dev Adm, Dept Agrofood Resources, Jeonju, South Korea
关键词
Black soybean; germination; high hydrostatic pressure; phenolic compound; estrogenic activity; IN-VITRO; ANTIOXIDANT ACTIVITY; SOY ISOFLAVONES; PHYTOESTROGENS; PURIFICATION; METABOLISM; WOMEN;
D O I
10.1080/08957959.2018.1459599
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We investigated the influence of high hydrostatic pressure (HHP) treatment on the estrogenic properties and conversion of the phenolic compounds in germinated black soybean. The black soybean was germinated for two- or four-days, and then subjected to HHP at 0.1, 50, 100, or 150MPa for 12 or 24h. The highest total polyphenol content (3.9mg GAE/g), flavonoid content (0.8mgCE/g), phenolic acid content (940 +/- 18.96g/g), and isoflavonone content (2600g/g) were observed after germination for four days and HHP treatment at 100MPa for 24h. In terms of isoflavone composition, the malonyl, acetyl and -glycoside contents decreased, while the aglycone content increased with HHP. The highest proliferative effect (150%) is observed at four days germination and HHP treatment at 100MPa. These results suggest that application of HHP may provide useful information regarding the utility of black soybean as alternative hormone replacement therapy.
引用
收藏
页码:177 / 192
页数:16
相关论文
共 36 条
[1]   In vitro antioxidant activity of anthocyanins of black soybean seed coat in human low density lipoprotein (LDL) [J].
Astadi, Ignasius Radix ;
Astuti, Mary ;
Santoso, Umar ;
Nugraheni, Prihati Sih .
FOOD CHEMISTRY, 2009, 112 (03) :659-663
[2]   Phytoestrogens and breast cancer [J].
Barnes, S .
BAILLIERES CLINICAL ENDOCRINOLOGY AND METABOLISM, 1998, 12 (04) :559-579
[3]   Tannin interactions with a full-length human salivary proline-rich protein display a stronger affinity than with single proline-rich repeats [J].
Charlton, AJ ;
Baxter, NJ ;
Lilley, TH ;
Haslam, E ;
McDonald, CJ ;
Williamson, MP .
FEBS LETTERS, 1996, 382 (03) :289-292
[5]   Processed sweet corn has higher antioxidant activity [J].
Dewanto, V ;
Wu, XZ ;
Liu, RH .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2002, 50 (17) :4959-4964
[6]   Two hormone replacement therapy (HRT) regimens for middle-eastern postmenopausal women [J].
Elfituri, A ;
Sherif, F ;
Elmahaishi, M ;
Chrystyn, H .
MATURITAS, 2005, 52 (01) :52-59
[7]  
Fengzhong Wang, 2015, Journal of Functional Foods, V14, P596
[8]  
Gross G.G., 1985, Biosynthesis and biodegradation of wood components, P229, DOI DOI 10.1016/B978-0-12-347880-1.50014-3
[9]   PHYSIOLOGY AND MOLECULAR-BIOLOGY OF PHENYLPROPANOID METABOLISM [J].
HAHLBROCK, K ;
SCHEEL, D .
ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY, 1989, 40 :347-369
[10]   COATED CHARCOAL IMMUNOASSAY OF INSULIN [J].
HERBERT, V ;
LAU, KS ;
GOTTLIEB, CW ;
BLEICHER, SJ .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1965, 25 (10) :1375-+