Genomics to fluxomics and physiomics - pathway engineering

被引:46
作者
Sanford, K [1 ]
Soucaille, P [1 ]
Whited, G [1 ]
Chotani, G [1 ]
机构
[1] Genencor Int Inc, Palo Alto, CA 94304 USA
关键词
D O I
10.1016/S1369-5274(02)00318-1
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Developments in microanalytical methods are enabling quantitative measurement of multiple metabolic fluxes and, in conjunction with transcript and proteomic profiling, are revolutionizing the ability of researchers to manipulate metabolism through pathway engineering in a variety of species. We review recent literature on the advances in genomics, proteomics, fluxomics and computational modeling focused on metabolic pathway engineering applications.
引用
收藏
页码:318 / 322
页数:5
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