ENZYME-MEDIATED SELF-ASSEMBLY OF HIGHLY ORDERED STRUCTURES FROM DISORDERED PROTEINS

被引:0
|
作者
Athamneh, Ahmad [1 ]
Barone, Justin [1 ]
机构
[1] Virginia Tech, Dept Biol Syst Engn, Blacksburg, VA 24061 USA
关键词
AMYLOID-LIKE FIBRILS; OVALBUMIN;
D O I
暂无
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Trypsin hydrolysis of wheat gluten produced glutamine-rich short peptides with a tendency to self-assemble into supermolecular structures extrinsic to native wheat gluten. Fourier transform infrared and X-ray diffraction data suggested that the new structures formed resembled that of cross-beta amyloid fibrils found in some insect silk and implicated in prion diseases. The superstructures were about 10 mu m in diameter with clear right-handed helical configuration and appeared to be bundles of smaller fibrils of about 63 nm in diameter. Results demonstrate the potential for utilizing cheap protein sources and natural mechanisms of protein self-assembly to design advanced nanomaterials that can provide a wide range of structural and chemical functionality.
引用
收藏
页码:625 / 628
页数:4
相关论文
共 50 条
  • [1] Enzyme-mediated self-assembly of highly ordered structures from disordered proteins
    Athamneh, Ahmad I.
    Barone, Justin R.
    SMART MATERIALS AND STRUCTURES, 2009, 18 (10)
  • [2] Enzyme-mediated intratumoral self-assembly of nanotheranostics for enhanced imaging and tumor therapy
    Yuan, Yue
    Bulte, Jeff W. M.
    WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2022, 14 (04)
  • [3] Formation of TiO2 nanostructures by enzyme-mediated self-assembly for the destruction of macrophages
    Department of Anatomy and Cell Biology, Institute of Health Biosciences, University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
    不详
    不详
    Chem. Mater., 14 (3341-3347):
  • [4] Improved enzyme-mediated synthesis and supramolecular self-assembly of naturally occurring conjugates of β-sitosterol
    Wimmerova, Martina
    Siglerova, Vera
    Saman, David
    Slouf, Miroslav
    Kaletova, Eva
    Wimmer, Zdenek
    STEROIDS, 2017, 117 : 38 - 43
  • [5] Formation of TiO2 Nanostructures by Enzyme-Mediated Self-Assembly for the Destruction of Macrophages
    Hayashi, Koichiro
    Nakamura, Michihiro
    Sakamoto, Wataru
    Yogo, Toshinobu
    Kori, Toshinari
    Ishimura, Kazunori
    CHEMISTRY OF MATERIALS, 2011, 23 (14) : 3341 - 3347
  • [6] Enzyme-mediated assembly of chimeric membrane proteins at phospholipid bilayers
    Scott, D.
    Tullman, J.
    Kelman, Z.
    Marino, J.
    Silin, V
    ENGINEERING REPORTS, 2019, 1 (02)
  • [7] THE SELF-ASSEMBLY OF A HIGHLY ORDERED [2]CATENANE
    ASHTON, PR
    BROWN, CL
    CHRYSTAL, EJT
    GOODNOW, TT
    KAIFER, AE
    PARRY, KP
    PHILP, D
    SLAWIN, AMZ
    SPENCER, N
    STODDART, JF
    WILLIAMS, DJ
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (09) : 634 - 639
  • [8] Enzyme-Mediated In Situ Self-Assembly Promotes In Vivo Bioorthogonal Reaction for Pretargeted Multimodality Imaging
    Hu, Yuxuan
    Zhang, Junya
    Miao, Yinxing
    Wen, Xidan
    Wang, Jian
    Sun, Yidan
    Chen, Yinfei
    Lin, Jianguo
    Qiu, Ling
    Guo, Kai
    Chen, Hong-Yuan
    Ye, Deju
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (33) : 18082 - 18093
  • [9] Self-assembly of active core corona particles into highly ordered and self-healing structures
    Du, Yunfei
    Jiang, Huijun
    Hou, Zhonghuai
    JOURNAL OF CHEMICAL PHYSICS, 2019, 151 (15):
  • [10] Highly ordered supramolecular structures from self-assembly of ionic surfactants in oppositely charged polyelectrolyte gels
    Zhou, SQ
    Yeh, FJ
    Burger, C
    Chu, B
    SCATTERING FROM POLYMERS: CHARACTERIZATION BY X-RAYS, NEUTRONS, AND LIGHT, 2000, 739 : 244 - 260